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March 01, 1992; 42 (3) Articles

Multifocal demyelinating motor neuropathy

Cranial nerve involvement and immunoglobulin therapy

Ryuji Kaji, Hiroshi Shibasaki, Jun Kimura
First published March 1, 1992, DOI: https://doi.org/10.1212/WNL.42.3.506
Ryuji Kaji
MD, PhD
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Hiroshi Shibasaki
MD
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Jun Kimura
MD
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Citation
Multifocal demyelinating motor neuropathy
Cranial nerve involvement and immunoglobulin therapy
Ryuji Kaji, Hiroshi Shibasaki, Jun Kimura
Neurology Mar 1992, 42 (3) 506; DOI: 10.1212/WNL.42.3.506

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Abstract

We report two patients with multifocal demyelinating motor neuropathy whose symptoms improved after immunoglobulin infusion. Clinical signs included atrophy of the tongue and limb muscles, closely resembling that of motor neuron disease. Nerve conduction studies revealed multiple sites of motor conduction block without sensory abnormalities, suggesting selective involvement of motor fibers. Careful documentation of conduction block is required to diagnose this entity, which may be treated with immunoglobulin therapy.

  • © 1992 by AAN Enterprises, Inc.

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