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Smoking independently increases risk for aneurysm rupture and aneurysm formation.1,2 It may weaken the wall of intracranial aneurysms due to inflammation, making them more vulnerable to trigger factors and therefore to rupture.3 Previous studies have assessed the effect of current smoking. In this issue of Neurology®, Can et al.4 assess the effect of both smoking intensity and duration on intracranial aneurysm rupture.
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