This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
We support the findings of Goyal et al.,1 which showed that IV thrombolysis pretreatment improves outcomes in patients with large vessel occlusion (LVO) undergoing mechanical thrombectomy. We agree that reasons may include protection from infarct in new territory (INT) in thrombolysis recipients,2 as suggested in a post hoc analysis of the Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) trial.3 We propose that INT should be systematically studied as a secondary outcome in any trials of combined thrombolysis/thrombectomy vs thrombectomy alone to further clarify this issue.
Footnotes
Author disclosures are available upon request (journal{at}neurology.org).
- © 2018 American Academy of Neurology
AAN Members: Sign in with your AAN member credentials (e-mail or 6-digit Member ID number)
Non-AAN Member subscribers: Sign in with subscriber credentials
Log in using your username and password
Purchase access
Disputes & Debates: Rapid online correspondence
NOTE: All contributors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.
- Stay timely. Submit only on articles published within the last 8 weeks.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- 200 words maximum.
- 5 references maximum. Reference 1 must be the article on which you are commenting.
- 5 authors maximum. Exception: replies can include all original authors of the article.
- Submitted comments are subject to editing and editor review prior to posting.