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April 04, 2023; 100 (14) Clinical/Scientific Note

Biological Sex Differences in Risk Factors and Outcomes Among Hospitalized Adults With Stroke in Lusaka, Zambia

Aparna Nutakki, Mashina Chomba, Lorraine Chishimba Chishimba, Stanley Zimba, Rebecca F. Gottesman, Mona N. Bahouth, Deanna R. Saylor
First published December 19, 2022, DOI: https://doi.org/10.1212/WNL.0000000000201696
Aparna Nutakki
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Mashina Chomba
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Lorraine Chishimba Chishimba
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Stanley Zimba
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Rebecca F. Gottesman
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Mona N. Bahouth
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Deanna R. Saylor
From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
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Citation
Biological Sex Differences in Risk Factors and Outcomes Among Hospitalized Adults With Stroke in Lusaka, Zambia
Aparna Nutakki, Mashina Chomba, Lorraine Chishimba Chishimba, Stanley Zimba, Rebecca F. Gottesman, Mona N. Bahouth, Deanna R. Saylor
Neurology Apr 2023, 100 (14) 666-669; DOI: 10.1212/WNL.0000000000201696

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Article Information

vol. 100 no. 14 666-669
DOI: 
https://doi.org/10.1212/WNL.0000000000201696
PubMed: 
36535774

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received May 2, 2022
  • Accepted in final form November 1, 2022
  • First Published December 19, 2022.

Article Versions

  • Previous version (December 19, 2022 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government.

Author Disclosures

    1. Aparna Nutakki, BA,
    2. Mashina Chomba, MBChB, MMed,
    3. Lorraine Chishimba Chishimba, MMED,
    4. Stanley Zimba, MMED, STP,
    5. Rebecca F. Gottesman, MD, PhD,
    6. Mona N. Bahouth, MD, PhD and
    7. Deanna R. Saylor, MD, MHS
  1. Aparna Nutakki, BA,
  2. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. None

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. 1) National Institute of Health UJMT Fogarty Global <br>Health Fellowship, 2019-2020

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. 1) Gold Humanism Student Summer Fellowship

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Mashina Chomba, MBChB, MMed,
  4. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. None

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1) Multiple Sclerosis International <br>Federation

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Lorraine Chishimba Chishimba, MMED,
  6. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. Encephalitis Society: Funding for travel to the Encephalitis <br>Society Conference at Royal College of Physicians in December <br>2019

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. 1. Global Health Institute Northwestern University for <br>Parkinson's disease study<br><br>2. International Parkinson Disease Genomics Consortium - <br>Africa. University College London for Parkinson's disease <br>study<br><br>3. Zambia Intracerebral Heamorrhage Prediction Study - Stroke <br>study

    Research Support, Foundations and Societies:
    1. None

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Stanley Zimba, MMED, STP,
  8. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. None

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. None

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Rebecca F. Gottesman, MD, PhD,
  10. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. None

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Former recipient: National Institutes of Health/ National <br><br>Institute on<br><br><br><br>Aging. 1R01AG040282, Principal Investigator, 9/2011-8/2021<br><br><br><br>RF1 AG050745, Multiple Principal Investigator, 4/2016-3/2021<br><br><br><br>NIH/NIH K24 AG052573, Principal Investigator<br><br><br><br>NIH (NHLBI/NIA/NINDS) U01 HL096812, Principal Investigator, <br><br>12/1/2019-<br><br><br><br>11/30/2023 (PI only through May 2021)

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. None

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Mona N. Bahouth, MD, PhD and
  12. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. None

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. American Heart Association Innovative Project Award

    Research Support, Government Entities:
    1. NIH Fogarty R21

    Research Support, Academic Entities:
    1. Johns Hopkins School of Medicine, Richard Starr Ross <br>Clinician Scientist Award

    Research Support, Foundations and Societies:
    1. None

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Deanna R. Saylor, MD, MHS
  14. Scientific Advisory Boards:
    1. None

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. None

    Editorial Boards:
    1. Neuorology, Co-Editor, Without Borders section, 15 July <br>2022-Present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. I serve as unpaid member of several working groups for the <br>Multiple Sclerosis International Federation including their <br>International Working Group on Access, Mission/Vision <br>Committee, and Minimal Essential Medications Panel.

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) NIH, MH120693-01, Co-investigator, 2019-2024; (2) NIH, <br>NS094037-05S1, Co-investigator, 2019-2021; (3) NIH, <br>AG059504-01A1, Co investigator, 2019-2024; (4) NIH, <br>MH075673, Co-investigator, 2017-2022; (5) NIH, NS118543-01, <br>Co-investigator, 2020-2022; (6) NIH, 1K01 TW011771-01A1

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1) National Multiple Sclerosis Society<br>(2) American Academy of Neurology

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD
  1. Correspondence
    Dr. Saylor deanna{at}jhmi.edu
View Full Text

Article usage

Article usage: December 2022 to May 2023

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Letters: Rapid online correspondence

  • Reader Response: Biological Sex Differences in Risk Factors and Outcomes Among Hospitalized Adults With Stroke in Lusaka, Zambia
    • Emma D. Frost, Medical Student, Cooper Medical School of Rowan University
    • James E. Siegler, Director, Comprehensive Stroke Program, NeuroHospitalist, Cooper University Hospital
    Submitted February 02, 2023
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