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February 14, 2023; 100 (7) NeuroImage

Primary Melanocytoma Arising From Trigeminal Nerve

Jun Liu, Wenjun Zhang, Xinyun Ye, Si Zhang, Qiuhua Jiang
First published November 28, 2022, DOI: https://doi.org/10.1212/WNL.0000000000201570
Jun Liu
From the Department of Neurosurgery (J.L., X.Y., Q.J.), and Department of Recovery Medicine (W.Z.), The Affiliated Ganzhou Hospital of Nanchang University, Jiangxi, China; and Department of Neurosurgery (S.Z.), West China Hospital of Sichuan University, Chengdu.
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Wenjun Zhang
From the Department of Neurosurgery (J.L., X.Y., Q.J.), and Department of Recovery Medicine (W.Z.), The Affiliated Ganzhou Hospital of Nanchang University, Jiangxi, China; and Department of Neurosurgery (S.Z.), West China Hospital of Sichuan University, Chengdu.
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Xinyun Ye
From the Department of Neurosurgery (J.L., X.Y., Q.J.), and Department of Recovery Medicine (W.Z.), The Affiliated Ganzhou Hospital of Nanchang University, Jiangxi, China; and Department of Neurosurgery (S.Z.), West China Hospital of Sichuan University, Chengdu.
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Si Zhang
From the Department of Neurosurgery (J.L., X.Y., Q.J.), and Department of Recovery Medicine (W.Z.), The Affiliated Ganzhou Hospital of Nanchang University, Jiangxi, China; and Department of Neurosurgery (S.Z.), West China Hospital of Sichuan University, Chengdu.
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Qiuhua Jiang
From the Department of Neurosurgery (J.L., X.Y., Q.J.), and Department of Recovery Medicine (W.Z.), The Affiliated Ganzhou Hospital of Nanchang University, Jiangxi, China; and Department of Neurosurgery (S.Z.), West China Hospital of Sichuan University, Chengdu.
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Citation
Primary Melanocytoma Arising From Trigeminal Nerve
Jun Liu, Wenjun Zhang, Xinyun Ye, Si Zhang, Qiuhua Jiang
Neurology Feb 2023, 100 (7) 342-343; DOI: 10.1212/WNL.0000000000201570

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A 12-year-old girl presented with a 3-week history of left-sided hemifacial pain. Physical examination revealed hemifacial numbness, hypesthesia, and chewing weakness without signs of nevus of Ota. Neuroradiologic examinations showed a dumbbell-shaped lesion in middle and posterior fossa along the distribution of the trigeminal nerve (Figure 1). Intraoperatively, a well-defined black extra-axial lesion firmly attached to the trigeminal nerve was observed. Pathologic examination confirmed a melanocytoma (Figure 2). Extra-axial melanocytoma may have a tendency to distribute along the trigeminal nerve similar to nevus of Ota. For lesions involving the trigeminal nerve with hyperdensity on CT and hyperintensity on T1 and hypointensity in T2 imaging, melanocytoma should be considered.1

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  • ↵* These authors contributed equally to this work as co-first authors.

  • ↵† These authors contributed equally to this work as co-senior authors.

  • Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

  • Submitted and editor reviewed. The handling editor was Editor-in-Chief José G. Merino, MD, MPhil, FAHA, FAAN.

  • Received July 11, 2022.
  • Accepted in final form September 28, 2022.
  • © 2022 American Academy of Neurology
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