Abstract
Among 45,000 pregnant women, 21.4 per 1000 (2.1%) reported at least one seizure before or during pregnancy. During the study pregnancy, 4.4 per 1000 had a noneclamptic seizure, and another 4.5 per 1000 had one in the 5 years preceding the study.
Stillbirth, microcephaly, mental retardation, and nonfebrile seizure disorders occurred with heightened frequency in the offspring of women with seizure disorders; low birthweight, neonatal seizures, and first-year deaths were not more common. Approximately 80% of the women with seizure disorders had infants with none of the unfavorable outcomes studied.
The observational nature of this and other clinical studies on this topic makes it difficult to evaluate the role of medical therapy in the outcome.
- © 1982 by the American Academy of Neurology
Letters: Rapid online correspondence
REQUIREMENTS
If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Hemiplegic Migraine Associated With PRRT2 Variations A Clinical and Genetic Study
Dr. Robert Shapiro and Dr. Amynah Pradhan