The design of clinical studies to assess the efficacy and toxicity of antiepileptic drugs

• Historical perspective on the choice of antiepileptic drugs for the treatment of seizures in adults

  Dennis B. Smith, Antonio V. Delgado Escueta, Joyce A. Cramer, Richard H. Mattson

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• Principles in designing clinical trials for antiepileptic drugs

  Antonio V. Delgado Escueta, Richard H. Mattson, Dennis B. Smith, Joyce A. Cramer, Joseph F. Collins

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• A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults

  Richard H. Mattson, Joyce A. Cramer, Antonio V. Delgado Escueta, Dennis B. Smith, Joseph F. Collins, VA Epilepsy Cooperative Study Group, Thomas R. Browne, Wayne E. Crill, Richard W. Homan, Assa Mayersdoif, Charlotte B. McCutchen, James O. McNamara, N. Paul Rosenthal, David M. Treiman, B. Joe Wilder, Peter D. Williamson, Larry M. Young

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• A method of quantification for the evaluation of antiepileptic drug therapy

  Joyce A. Cramer, Dennis B. Smith, Richard H. Mattson, Antonio V. Delgado Escueta, Joseph F. Collins, VA Epilepsy Cooperative Study Group, Thomas R. Browne, Wayne E. Crill, Richard W. Homan, Assa Mayersdorf, Charlotte B. McCutchen, James O. McNamara, N. Paul Rosenthal, David M. Treiman, B. Joe Wilder, Peter D. Williamson

  • Abstract
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