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December 01, 1990; 40 (12) Brief Communications

Acute axonal polyneuropathy associated with anti‐GM1 antibodies following Campylobacter enteritis

Nobuhiro Yuki, Hiide Yoshino, Shuzo Sato, Tadashi Miyatake
First published December 1, 1990, DOI: https://doi.org/10.1212/WNL.40.12.1900
Nobuhiro Yuki
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Hiide Yoshino
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Shuzo Sato
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Tadashi Miyatake
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Citation
Acute axonal polyneuropathy associated with anti‐GM1 antibodies following Campylobacter enteritis
Nobuhiro Yuki, Hiide Yoshino, Shuzo Sato, Tadashi Miyatake
Neurology Dec 1990, 40 (12) 1900; DOI: 10.1212/WNL.40.12.1900

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Abstract

We report 2 patients with Guillain-Barré syndrome (GBS) following Campylobacter jejuni enteritis. Electrophysiologic studies indicated that the predominant process was axonal degeneration of motor nerves, and clinical recovery was poor. Serum testing by thin-layer chromatography and enzyme-linked immunosorbent assay revealed that the sera from both patients contained high titers of IgG antibody against GM1 ganglioside. These cases may represent a subgroup of GBS as acute axonal polyneuropathy following C jejuni enteritis associated with anti-GM1 antibodies.

  • © 1990 by the American Academy of Neurology

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