October 01, 1996; 47 (4) ARTICLES
Fibroblasts of patients affected by Down's syndrome oversecrete amyloid precursor protein and are hyporesponsive to protein kinase C stimulation
S. Govoni, S. Bergamaschi, L. Gasparini, C. Quaglia, M. Racchi, E. Cattaneo, G. Binetti, A. Bianchetti, F. Giovetti, F. Battaini, M. Trabucchi
First published October 1, 1996, DOI: https://doi.org/10.1212/WNL.47.4.1069
S. Govoni
S. Bergamaschi
L. Gasparini
C. Quaglia
M. Racchi
E. Cattaneo
G. Binetti
A. Bianchetti
F. Giovetti
F. Battaini
Fibroblasts of patients affected by Down's syndrome oversecrete amyloid precursor protein and are hyporesponsive to protein kinase C stimulation
S. Govoni, S. Bergamaschi, L. Gasparini, C. Quaglia, M. Racchi, E. Cattaneo, G. Binetti, A. Bianchetti, F. Giovetti, F. Battaini, M. Trabucchi
Neurology Oct 1996, 47 (4) 1069-1075; DOI: 10.1212/WNL.47.4.1069
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vol. 47 no. 4 1069-1075
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History:
- First Published October 1, 1996.
Copyright & Usage:
Copyright 1996 by Advanstar Communications Inc.
Author Disclosures
- S. Govoni, PhD,
- S. Bergamaschi, PhD,
- L. Gasparini, PhD,
- C. Quaglia, PhD,
- M. Racchi, PhD,
- E. Cattaneo, PhD,
- G. Binetti, MD,
- A. Bianchetti, MD,
- F. Giovetti, MD,
- F. Battaini, PhD and
- M. Trabucchi, MD
- S. Govoni, PhD,
- S. Bergamaschi, PhD,
- L. Gasparini, PhD,
- C. Quaglia, PhD,
- M. Racchi, PhD,
- E. Cattaneo, PhD,
- G. Binetti, MD,
- A. Bianchetti, MD,
- F. Giovetti, MD,
- F. Battaini, PhD and
- M. Trabucchi, MD
- From the Institute of Pharmacology (Dr. Govoni), University of Pavia; Institute of Pharmacological Sciences (Drs. Bergamaschi, Gasparini, Quaglia, Racchi, and Cattaneo), University of Milano; Alzheimer's Department (Drs. Racchi, Binetti, and Bianchetti), Sacred Heart Hospital of Brescia; Hospital Institute of Sospiro (Dr. Giovetti), Cremona; and the Department of Experimental Medicine and Biochemical Sciences (Drs. Battaini and Trabucchi), University of Roma Tor Vergata, Italy.
- Supported by grants from the Regione Lombardia and the Ministry of Health of Italy.
- Received September 22, 1995. Accepted in final form February 13, 1996.
- Address correspondence and reprint requests to Dr. Stefano Govoni, c/o Institute of Pharmacological Sciences, Univ. of Milano, Via Balzaretti 9, 20133 Milano, Italy.
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