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October 01, 1996; 47 (4) ARTICLES

Fibroblasts of patients affected by Down's syndrome oversecrete amyloid precursor protein and are hyporesponsive to protein kinase C stimulation

S. Govoni, S. Bergamaschi, L. Gasparini, C. Quaglia, M. Racchi, E. Cattaneo, G. Binetti, A. Bianchetti, F. Giovetti, F. Battaini, M. Trabucchi
First published October 1, 1996, DOI: https://doi.org/10.1212/WNL.47.4.1069
S. Govoni
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S. Bergamaschi
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L. Gasparini
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C. Quaglia
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M. Racchi
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E. Cattaneo
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G. Binetti
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A. Bianchetti
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F. Giovetti
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F. Battaini
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M. Trabucchi
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Citation
Fibroblasts of patients affected by Down's syndrome oversecrete amyloid precursor protein and are hyporesponsive to protein kinase C stimulation
S. Govoni, S. Bergamaschi, L. Gasparini, C. Quaglia, M. Racchi, E. Cattaneo, G. Binetti, A. Bianchetti, F. Giovetti, F. Battaini, M. Trabucchi
Neurology Oct 1996, 47 (4) 1069-1075; DOI: 10.1212/WNL.47.4.1069

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Article Information

vol. 47 no. 4 1069-1075
DOI: 
https://doi.org/10.1212/WNL.47.4.1069
PubMed: 
8857747

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • First Published October 1, 1996.

Copyright & Usage: 
Copyright 1996 by Advanstar Communications Inc.

Author Disclosures

    1. S. Govoni, PhD,
    2. S. Bergamaschi, PhD,
    3. L. Gasparini, PhD,
    4. C. Quaglia, PhD,
    5. M. Racchi, PhD,
    6. E. Cattaneo, PhD,
    7. G. Binetti, MD,
    8. A. Bianchetti, MD,
    9. F. Giovetti, MD,
    10. F. Battaini, PhD and
    11. M. Trabucchi, MD
  1. S. Govoni, PhD,
  2. S. Bergamaschi, PhD,
  3. L. Gasparini, PhD,
  4. C. Quaglia, PhD,
  5. M. Racchi, PhD,
  6. E. Cattaneo, PhD,
  7. G. Binetti, MD,
  8. A. Bianchetti, MD,
  9. F. Giovetti, MD,
  10. F. Battaini, PhD and
  11. M. Trabucchi, MD
  1. From the Institute of Pharmacology (Dr. Govoni), University of Pavia; Institute of Pharmacological Sciences (Drs. Bergamaschi, Gasparini, Quaglia, Racchi, and Cattaneo), University of Milano; Alzheimer's Department (Drs. Racchi, Binetti, and Bianchetti), Sacred Heart Hospital of Brescia; Hospital Institute of Sospiro (Dr. Giovetti), Cremona; and the Department of Experimental Medicine and Biochemical Sciences (Drs. Battaini and Trabucchi), University of Roma Tor Vergata, Italy.
  2. Supported by grants from the Regione Lombardia and the Ministry of Health of Italy.
  3. Received September 22, 1995. Accepted in final form February 13, 1996.
  4. Address correspondence and reprint requests to Dr. Stefano Govoni, c/o Institute of Pharmacological Sciences, Univ. of Milano, Via Balzaretti 9, 20133 Milano, Italy.
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