Articles

• History of levodopa and dopamine agonists in Parkinson's disease treatment

  Eduardo Tolosa, Maria J. Martí, Francesc Valldeoriola, José L. Molinuevo

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• Mechanism of action of dopaminergic agents in Parkinson's disease

  William C. Koller, Miguel G. Rueda

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• Implications of the 5-year CR FIRST trial

  Rudy Capildeo

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• Initiating therapy for Parkinson's disease

  Dee E. Silver, Stefano Ruggieri

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• Adjuncts to levodopa therapyDopamine agonists

  Werner Poewe

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• Extending levodopa actionCOMT inhibition

  Pablo Martínez-Martín, Christopher F. O'Brien

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• Managing the neuropsychiatric symptoms of Parkinson's disease

  Abraham Lieberman

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• Levodopa neurotoxicityExperimental studies versus clinical relevance

  Peter G. Jenner, Mitchell F. Brin

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