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June 01, 1999; 52 (9) Views & Reviews

Applications of diffusion–perfusion magnetic resonance imaging in acute ischemic stroke

Marc Fisher, Gregory W. Albers
First published June 1, 1999, DOI: https://doi.org/10.1212/WNL.52.9.1750
Marc Fisher
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Gregory W. Albers
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Citation
Applications of diffusion–perfusion magnetic resonance imaging in acute ischemic stroke
Marc Fisher, Gregory W. Albers
Neurology Jun 1999, 52 (9) 1750; DOI: 10.1212/WNL.52.9.1750

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Abstract

Article abstract Diffusion-weighted imaging (DWI) and perfusion imaging (PI) are two new magnetic resonance technologies that are becoming increasingly available for evaluation of acute ischemic stroke patients. DWI provides information about the location of acute focal ischemic brain injury at early time points and PI can document the presence of disturbances in microcirculatory perfusion. DWI and PI are now being used in clinical practice and in clinical trials of potential acute stroke therapies to assess their utility. In the future, DWI and PI may aid in the development of effective acute stroke therapies and help identify which stroke patients are most likely to benefit from specific agents.

  • Received October 5, 1998.
  • Accepted March 17, 1999.
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  • Article
    • Abstract
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    • Applying DWI and PI to focal brain ischemia.
    • Relationship of DWI–PI to clinical neurologic outcomes and infarct volume.
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