Idiopathic intracranial hypertension
The prevalence and morphology of sinovenous stenosis
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Abstract
Objective: To determine the prevalence and nature of sinovenous obstruction in idiopathic intracranial hypertension (IIH) using auto-triggered elliptic-centric-ordered three-dimensional gadolinium-enhanced MR venography (ATECO MRV).
Methods: In a prospective controlled study, 29 patients with established IIH as well as 59 control patients underwent ATECO MRV. In a randomized blinded fashion, three readers evaluated the images. Using a novel scoring system, each reader graded the degree of stenosis seen in the transverse and sigmoid sinuses of each patient.
Results: There was excellent agreement across the three readers for application of the grading system. Substantial bilateral sinovenous stenoses were seen in 27 of 29 patients with IIH and in only 4 of 59 control patients.
Conclusion: Using ATECO MRV and a novel grading system for quantifying sinovenous stenoses, the authors can identify IIH patients with sensitivity and specificity of 93%.
- Received December 5, 2002.
- Accepted February 20, 2003.
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Disputes & Debates: Rapid online correspondence
- Reply to Williams and Bergui
- Richard I Farb, Toronto Western Hospital, 399 Bathurst Street Toronto Ontario Canada M5T 2S8richard.farb@utoronto.ca
- Richard I. Farb, M.D. Irene Vanek MD. James N. Scott M.D. David J. Mikulis, M.D. Robert A. Willinsky MD. George Tomlinson, PhD. Karel G. terBrugge MD.
Submitted September 15, 2003 - Idiopathic intracranial hypertension: The prevalence and morphology of sinovenous stenosis
- Mauro Bergui, Universita di Torino, Via Cherasco 15, 10126 Torino Italymauro.bergui@unito.it
- Gianni Boris Bradac, MD
Submitted September 15, 2003 - Idiopathic intracranial hypertension: The prevalence and morphology of sinovenous stenosis
- David T Williams, White Memorial Medical Center, 1720 Cesar E Chavez Ave, Internal Medicine Residency Office, LA, CA, 90033david@lemonchicken.com
- Antonio K Liu
Submitted September 15, 2003
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