March 14, 2006; 66 (5) Views & Reviews
Optimizing the ongoing search for new treatments for Parkinson disease
Using futility designs
B. C. Tilley, Y. Y. Palesch, K. Kieburtz, B. Ravina, P. Huang, J. J. Elm, K. Shannon, G. F. Wooten, C. M. Tanner, G. C. Goetz
First published March 13, 2006, DOI: https://doi.org/10.1212/01.wnl.0000201251.33253.fb
B. C. Tilley
Y. Y. Palesch
K. Kieburtz
B. Ravina
P. Huang
J. J. Elm
K. Shannon
G. F. Wooten
C. M. Tanner
Optimizing the ongoing search for new treatments for Parkinson disease
Using futility designs
B. C. Tilley, Y. Y. Palesch, K. Kieburtz, B. Ravina, P. Huang, J. J. Elm, K. Shannon, G. F. Wooten, C. M. Tanner, G. C. Goetz
Neurology Mar 2006, 66 (5) 628-633; DOI: 10.1212/01.wnl.0000201251.33253.fb
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vol. 66 no. 5 628-633
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History:
- First Published March 13, 2006.
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© 2006
Author Disclosures
- B. C. Tilley, PhD,
- Y. Y. Palesch, PhD,
- K. Kieburtz, MD,
- B. Ravina, MD,
- P. Huang, PhD,
- J. J. Elm, MA,
- K. Shannon, MD,
- G. F. Wooten, MD,
- C. M. Tanner, MD, PhD,
- G. C. Goetz, MD and
- on behalf of the NET-PD Investigators*
- B. C. Tilley, PhD,
- Y. Y. Palesch, PhD,
- K. Kieburtz, MD,
- B. Ravina, MD,
- P. Huang, PhD,
- J. J. Elm, MA,
- K. Shannon, MD,
- G. F. Wooten, MD,
- C. M. Tanner, MD, PhD,
- G. C. Goetz, MD and
- on behalf of the NET-PD Investigators*
- From the Department of Biostatistics, Bioinformatics & Epidemiology (B.C.T., Y.Y.P., P.H., J.J.E.), Medical University of South Carolina, Charleston; Department of Neurology (K.K.), University of Rochester, NY; NINDS (B.R.), National Institutes of Health, Bethesda, MD; Department of Neurological Sciences (K.S., G.C.G.), Rush-Presbyterian-St. Luke’s Medical Center, Chicago, IL; Department of Neurology (G.F.W.), University of Virginia Health Sciences Center, Charlottesville; and The Parkinson’s Institute (C.M.T.), Sunnyvale, CA.
- Address correspondence and reprint requests to Dr. Barbara C. Tilley, Department of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina, P.O. Box 250835, 135 Cannon Street, Suite 303, Charleston, SC 29425; e-mail: tilleybc{at}musc.edu
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