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March 06, 2007; 68 (10) Special Article

Assessment: Use of epidural steroid injections to treat radicular lumbosacral pain

Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

Carmel Armon, Charles E. Argoff, Jeffrey Samuels, Misha-Miroslav Backonja
First published March 5, 2007, DOI: https://doi.org/10.1212/01.wnl.0000256734.34238.e7
Carmel Armon
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Charles E. Argoff
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Jeffrey Samuels
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Misha-Miroslav Backonja
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Citation
Assessment: Use of epidural steroid injections to treat radicular lumbosacral pain
Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Carmel Armon, Charles E. Argoff, Jeffrey Samuels, Misha-Miroslav Backonja
Neurology Mar 2007, 68 (10) 723-729; DOI: 10.1212/01.wnl.0000256734.34238.e7

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Abstract

Based on the available evidence, the Therapeutics and Technology Assessment subcommittee concluded that 1) epidural steroid injections may result in some improvement in radicular lumbosacral pain when assessed between 2 and 6 weeks following the injection, compared to control treatments (Level C, Class I-III evidence). The average magnitude of effect is small and generalizability of the observation is limited by the small number of studies, highly selected patient populations, few techniques and doses, and variable comparison treatments; 2) in general, epidural steroid injection for radicular lumbosacral pain does not impact average impairment of function, need for surgery, or provide long-term pain relief beyond 3 months. Their routine use for these indications is not recommended (Level B, Class I-III evidence); 3) there is insufficient evidence to make any recommendation for the use of epidural steroid injections to treat radicular cervical pain (Level U).

Footnotes

  • See the conflict of interest statement at the end of the text.

    Received July 6, 2006. Accepted in final form December 1, 2006.

    Approved by the Therapeutics and Technology Assessment Subcommittee on July 28, 2006; by the Practice Committee on November 11, 2006; and by the AAN Board of Directors on December 7, 2006.

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Letters: Rapid online correspondence

  • Use of epidural steroid injections to treat radicular lumbosacral pain
    • Laxmaiah Manchikanti, CEO American Society of Interventional Pain Physicians, 81 Lakeview Drive, Paducah, KY 42001drm@asipp.org
    • Mark V Boswell, James Giordano, Eugene Kaplan
    Submitted July 15, 2007
  • Reply from the authors
    • Carmel Armon, M.D., M.H.S., Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199Carmel.Armon@bhs.org
    • Charles E. Argoff, M.D., Jeffrey Samuels, M.D., Misha-Miroslav Backonja, M.D.
    Submitted July 15, 2007
  • Assessment: Use of epidural steroid injections to treat radicular lumbosacral pain
    • Sheldon E. Jordan, Neurological Associates of West Los Angeles, 2811 Wilshire Blvd, Santa Monica, CA 90403shellyj@aol.com
    Submitted June 11, 2007
  • Reply from the authors
    • Carmel Armon, M.D., M.H.S., Baystate Medical Center, Springfield, MACarmel.Armon@bhs.org
    • Charles E. Argoff, M.D., Jeffrey Samuels, M.D., Misha-Miroslav Backonja, M.D.
    Submitted June 11, 2007
  • Assessment: Use of epidural steroid injections to treat radicular lumbosacral pain
    • William M. Landau, Washington University School of Medicine, 660 S. Euclid Ave, Saint Louis, MO 63110landauw@neuro.wustl.edu
    • Dewey A. Nelson
    Submitted May 08, 2007
  • Reply from the Authors
    • Carmel Armon, MD, M.H.S., Baystate Medical Center, Springfield, MA 01199Carmel.Armon@bhs.org
    • Charles E. Argoff, M.D., Jeffrey Samuels, M.D., Misha-Miroslav Backonja, M.D.
    Submitted May 08, 2007
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