Epilepsy-associated bone mineral density loss should be prevented
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Osteopenia and bone mineral density (BMD) loss is a major public health problem in the United States, and was the subject of a 2004 Surgeon General’s report.1 BMD loss and increased fracture risk among young adults with epilepsy is especially common—two to six times more frequent than in the general population,2 and yet screening for BMD loss among children, adolescents, and young adults with epilepsy is not standard of care. Most physicians typically consider osteopenia and BMD loss as occurring primarily among white, postmenopausal women, or those with specific medical conditions such as hyperthyroidism, renal disease, alcoholism, and among those who smoke cigarettes and take corticosteroids.3 Furthermore, routine screening for BMD loss among young people with epilepsy has not been widely practiced, in part, because we do not know when to begin screening, we have not established standardized screening and treatment protocols for specific at-risk subpopulations, and there are very few specific interventions with proven efficacy in clinical trials among children and young adults with epilepsy.4 Prevention …
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Disputes & Debates: Rapid online correspondence
- Epilepsy-associated bone mineral density loss should be prevented
- Mohamad A. Mikati, American University of Beirut Medical Center, Riad El-Solh, Beirut 1107 2020 Lebanonmamikati@aub.edu.lb
- Nour Ataya and Ghada El- Hajj Fuleihan
Submitted September 11, 2008 - Reply from the author
- Edwin Trevathan, MD, MPH, National Center on Birth Defects and Developmental Disabilities, CDC, Mailstop E-87, 1600 Clifton Road, N.E., Atlanta, GA 30333net1@cdc.gov
Submitted September 11, 2008
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