ISOLATED FACIAL AND BULBAR PARESIS: A PERSISTENT MANIFESTATION OF NEONATAL MYASTHENIA GRAVIS
Citation Manager Formats
Make Comment
See Comments

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
The differential diagnosis of congenital facial and bulbar paresis in toddlers includes myotonic dystrophy, congenital myopathies, congenital myasthenic syndromes, Moebius syndrome, and 22q11 deletion syndrome. We report on a 6-year-old boy with a history of neonatal hypotonia and severe feeding difficulties followed by persistent isolated facial and bulbar paresis of unknown etiology. When he was 3 years old, his mother was diagnosed with myasthenia gravis (MG) and we concluded that his condition was a rare and persistent manifestation of neonatal MG.
Case reports.
The boy presented with neonatal hypotonia and poor spontaneous movements without respiratory distress or arthrogryposis. Sucking was absent; he was tube fed for 2 weeks. His tone progressively improved; he walked at 13 months but prominent facial weakness and feeding difficulties persisted. He was referred to us at 30 months with severe dysarthria. There was no complaint of fatigue or weakness. At age 5 his weight was 10 kg (<p3), his height was 86 cm (p3), and he had no ptosis or ophthalmoplegia. He had facial weakness, a constantly open mouth, and a high arched palate (figure). The soft palate was immobile and speech was extremely nasal and dysarthric. The tongue was normal. He could not whistle or blow his cheeks. Limb muscle strength and …
AAN Members: Sign in with your AAN member credentials (e-mail or 6-digit Member ID number)
Non-AAN Member subscribers: Sign in with subscriber credentials
Log in using your username and password
Purchase access
AAN members must change their passwords on the AAN site
For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)
Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here
Purchase
Individual access to articles is available through the Add to Cart option on the article page.
Access for 1 day (from the computer you are currently using) is US$ 39.00.
Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means.
The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use. Distributing copies (electronic or otherwise) of the article is not allowed.
Disputes & Debates: Rapid online correspondence
NOTE: All authors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.
- Stay timely. Submit only on articles published within the last 8 weeks.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- 200 words maximum.
- 5 references maximum. Reference 1 must be the article on which you are commenting.
- 5 authors maximum. Exception: replies can include all original authors of the article.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Related Articles
- No related articles found.