This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
To the Editor:
The investigators of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study1 analyze the increased risk of hemorrhagic stroke in patients with a history of cerebrovascular disease treated with statins. Since statin use is associated with an increased risk of hemorrhagic stroke in patients with a history of cerebrovascular disease, this study is important because it identifies at-risk subgroups of patients.2
The authors emphasize that hemorrhagic stroke as an entry event is associated with hemorrhagic stroke during follow-up. Since patients with hemorrhagic stroke are usually not treated with statins for secondary prevention, this observation is of minor clinical importance. Far more interesting is the increased risk of hemorrhagic stroke in patients with lacunar stroke, caused by cerebral small vessel disease (hazard ratio [HR] 4.99, 95% confidence interval [CI] 1.71 to 14.61), treated with statins. The authors discuss that increased hemorrhagic strokes in small vessel disease might …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Hemiplegic Migraine Associated With PRRT2 Variations A Clinical and Genetic Study
Dr. Robert Shapiro and Dr. Amynah Pradhan