Targeting hematoma expansion in ICH
Illusions of hope or hope to disillusion
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And the greatest artist of ancient Greece would be determined in a contest between Zeuxis and Parrhasius. Zeuxis painted grapes so naturalistically that birds flew to peck at them. Victory seeming to be Zeuxis', he called on Parrhasius to draw back the curtain concealing his drawing. Only, the curtain was the painting itself! Zeuxis yielded the prize: he had deceived the birds, but Parrhasius had deceived him.
—Plinii, Naturalis Historiae
Several variables are associated with poor outcome and mortality after intracerebral hemorrhage (ICH).1 Among modifiable factors, hematoma expansion may have a predominant role, and has been the target of recent therapeutic trials in ICH. The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT) and Antihypertensive Treatment of Acute Cerebral Hemorrhage Study (ATACH-1) showed that intensive blood pressure (BP) lowering is associated with reduced hematoma expansion during the first 24 hours of …
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