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August 14, 2012; 79 (7) Articles

Measures of growth in children at risk for Huntington disease

Jessica K. Lee, Kathy Mathews, Bradley Schlaggar, Joel Perlmutter, Jane S. Paulsen, Eric Epping, Leon Burmeister, Peg Nopoulos
First published July 18, 2012, DOI: https://doi.org/10.1212/WNL.0b013e3182648b65
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Article Information

vol. 79 no. 7 668-674
DOI: 
https://doi.org/10.1212/WNL.0b013e3182648b65
PubMed: 
22815549
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received October 5, 2011
  • Accepted January 23, 2012
  • First Published July 18, 2012.

Article Versions

Copyright & Usage: 
Copyright © 2012 by AAN Enterprises, Inc.

Author Disclosures

    1. Jessica K. Lee, MA,
    2. Kathy Mathews, MD,
    3. Bradley Schlaggar, MD, PhD,
    4. Joel Perlmutter, MD,
    5. Jane S. Paulsen, PhD,
    6. Eric Epping, MD, PhD,
    7. Leon Burmeister, PhD and
    8. Peg Nopoulos, MD
  1. Jessica K. Lee, MA,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Kathy Mathews, MD,
    3. Scientific Advisory Boards:

    1. FSH society, SAB member; DSMB member, Seaside Therapeutics; PPMD, Advisory Board member

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. PTC Therapeutics, clinical trial site PI, 2008-2012

    Research Support, Government Entities:

    1. NIH grant #U54 NS053672-06(Muscular Dystrophy Cooperative Research Center), project PI (2010-2012); Centers for Disease Control and Prevention, co-PI for site (2011-2014)

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. Friedreich’s Ataxia Research Alliance, site PI (2007- 2012); Parent Project Muscular Dystrophy, PI, (2011-2012)

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Bradley Schlaggar, MD, PhD,
    4. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Developmental Psychology, Editorial Advisory Board, 2010-present; Developmental Cognitive Neuroscience, Editorial Advisory Board, 2010-present

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. John Merck Fund Scholars Program Advisory Panel Speakers’ Bureaus: Tourette Syndrome Association

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH/NICHHD R01 HD057076, PI (2008-2013); NIH/NIBIB R01 EB009223, Co-I (2009-2014); NIH/NINDS K12NS001690 , PI (2009-2014); NIH R21 MH091512, PI (2010-2012); NIH/NICHD 1 P30 HD062171-01 Core D, Imaging Scientist (2010-2015); NIH/NIMH U54 MH091657, Co-I (2010-2015)

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. Tourette Syndrome Association, Inc., PI (2010-2012); McDonnell Foundation, Co-I (2011-2013)

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. Joel Perlmutter, MD,
    5. Scientific Advisory Boards:

    1. American Parkinson Disease Association, Scientific Advisory Board, currently, no compensation; Dystonia Medical Research Foundation, Medical and Scientific Advisory Board, no compensation; MO Chapter of the Dystonia Medical Research Fund, medical advisory board, no compensation; Greater St. Louis Chapter of the APDA, medical advisory board, no compensation

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. 1. U Louisville, honorarium; 2. Toronto Western Hospital, honorarium; 3. U Maryland, honorarium; 4. Weil Cornell School of Medicine, honorarium; 5. U Saskatoon, honorarium; 6. Movement Disorders Society, honorarium; 7. Society of Nuclear Medicine, honorarium

    Editorial Boards:

    1. Neurology, Editorial Board, no compensation, currently; Movement Disorders Journal, 2003-2008, no compensation

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. Parkinson Disease Study Group, paid for grant reviews, 2008, 2009, 2010, 2011; Medtronic Inc, partial fellowship support $25,000/yr 2006-2009

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Medtronic Inc, 2006-2009, provided partial fellowship support; Express Scripts, 2011, provided research support for investigation of phase 4 clinical trials

    Research Support, Government Entities:

    1. NIH RO1 NS41509, PI (2001-2016); NIH RO1 NS050425, PI (2005 - 2011); NIH RO1 NS058714, PI (2008 -2012); NIH RO1 NS075321, PI

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. Huntington Disease Society of American Center of Excellence; MJ Fox Foundation; CHDI (was HiQ Foundation); McDonnell Center for Higher Brain Function; Greater St. Louis Chapter of the American Parkinson Disease Association; American Parkinson Disease Association; APDA Advanced PD Research Center at Washington University; BJH Foundation

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. Gave deposition requested by defense attorney (defending a railroad and I was paid by the defense attorney) regarding a work-related injury sustained by one of my patients who is the plaintiff. 2011

  5. Jane S. Paulsen, PhD,
    6. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. CHDI Foundation, Inc.; Jane Paulsen, Principal Investigator; funding from CHDI since May, 2002

    Research Support, Government Entities:

    1. National Institutes for Health, National Institute of Neurological Disorders and Stroke (grant number NS40068); Jane Paulsen, Principal Investigator; funding from NIH since April, 2000

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  6. Eric Epping, MD, PhD,
    7. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH award to the University of Iowa Institute for Clinical and Translational Science, KL2RR024980, KL2 trainee, 2009-2011

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NARSAD Young Investigator Award (2008-present); Nellie Ball Trust (2008-present); CHDI Foundation, Inc (2009-present)

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  7. Leon Burmeister, PhD and
    8. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  8. Peg Nopoulos, MD
    9. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers’ Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIDCR, PI, 2009-2013 NIH, Ph, 2008-2013

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. CHDI

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Departments of Psychiatry (J.K.L., J.S.P., E.E., P.N.), Pediatrics (K.M., P.N.), and Neurology (K.M., J.S.P., P.N.), University of Iowa Carver College of Medicine, Iowa City; Departments of Radiology (B.S., J.P.), Pediatrics (B.S., J.P.), Anatomy & Neurobiology (B.S., J.P.), and Neurology (B.S., J.P.), and Program in Occupational Therapy (J.P.), Washington University School of Medicine, St. Louis, MO; Department of Psychology (J.S.P.), University of Iowa, Iowa City; and University of Iowa College of Public Health Administration (L.B.), Iowa City.
  1. Correspondence & reprint requests to Jessica Lee: jessica-k-lee{at}uiowa.edu
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