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August 28, 2012; 79 (9) Editorials

Small ischemic lesions following intracerebral hemorrhage

Silent but deadly

Shyam Prabhakaran, Kevin N. Sheth
First published July 25, 2012, DOI: https://doi.org/10.1212/WNL.0b013e3182648a8c
Shyam Prabhakaran
From the Department of Neurological Sciences (S.P.), Rush University Medical Center, Chicago, IL; and Departments of Neurology, Neurosurgery, and Emergency Medicine, Shock Trauma and Anesthesiology Research Center (STAR) (K.N.S.), University of Maryland School of Medicine, Baltimore. S.P. is currently with the Department of Neurology, Northwestern University, Chicago.
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Kevin N. Sheth
From the Department of Neurological Sciences (S.P.), Rush University Medical Center, Chicago, IL; and Departments of Neurology, Neurosurgery, and Emergency Medicine, Shock Trauma and Anesthesiology Research Center (STAR) (K.N.S.), University of Maryland School of Medicine, Baltimore. S.P. is currently with the Department of Neurology, Northwestern University, Chicago.
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Small ischemic lesions following intracerebral hemorrhage
Silent but deadly
Shyam Prabhakaran, Kevin N. Sheth
Neurology Aug 2012, 79 (9) 838-839; DOI: 10.1212/WNL.0b013e3182648a8c

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Diffusion-weighted imaging (DWI) has revolutionized stroke diagnosis with its ability to detect small areas of brain ischemia within 30 minutes of onset.1 Its application in ischemic stroke and TIA has provided insights into etiology and prognosis.2 Following intracerebral hemorrhage (ICH), the occurrence of ischemia has been sought for decades, focused primarily in the peri-hematomal region. Now, using DWI, we have emerging evidence that ischemia occurs in this setting and, furthermore, appears to be associated with outcome. The pathophysiology of restricted diffusion in …

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