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March 26, 2013; 80 (13) Article

Infectious burden and cognitive function

The Northern Manhattan Study

Mira Katan, Yeseon Park Moon, Myunghee Cho Paik, Ralph L. Sacco, Clinton B. Wright, Mitchell S.V. Elkind
First published March 25, 2013, DOI: https://doi.org/10.1212/WNL.0b013e3182896e79
Mira Katan
From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
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Yeseon Park Moon
From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
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Myunghee Cho Paik
From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
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Ralph L. Sacco
From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
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Clinton B. Wright
From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
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Mitchell S.V. Elkind
From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
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Full PDF
Citation
Infectious burden and cognitive function
The Northern Manhattan Study
Mira Katan, Yeseon Park Moon, Myunghee Cho Paik, Ralph L. Sacco, Clinton B. Wright, Mitchell S.V. Elkind
Neurology Mar 2013, 80 (13) 1209-1215; DOI: 10.1212/WNL.0b013e3182896e79

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Article Information

vol. 80 no. 13 1209-1215
DOI: 
https://doi.org/10.1212/WNL.0b013e3182896e79
PubMed: 
23530151

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received April 19, 2012
  • Accepted October 30, 2012
  • First Published March 25, 2013.

Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. Mira Katan, MD,
    2. Yeseon Park Moon, MS,
    3. Myunghee Cho Paik, PhD,
    4. Ralph L. Sacco, MD, MS,
    5. Clinton B. Wright, MD and
    6. Mitchell S.V. Elkind, MD, MS
  1. Mira Katan, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. Speaker Honoraria for presentation of data of the COSMOS study (Clinical Trials. gov number, NCT00390962) from BRAHMS,Berlin 2009.

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. I received within the last 3 years research grants from BRAHMS/ Thermo Fisher Scientific.

    Research Support, Government Entities:
    1. I received within the last 3 years research grants from the Swiss National Science Foundation (PBZHP3-130982)

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. I am receiving a transatlantic career award from the Fondation Leducq.

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Yeseon Park Moon, MS,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Myunghee Cho Paik, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Ralph L. Sacco, MD, MS,
  8. Scientific Advisory Boards:
    1. DSMB for AVERROES Trial through McMaster University Population Health Research Institue (indirect sponsor Pfizer)

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Ed Boards: Stroke, Neuroepidemiology

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Northern Manhattan Study, PI, 1993-present R37 NS29993 Family Study, PI, 2004-present R01 NS040807

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Evelyn McKnight Brain Institute

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Clinton B. Wright, MD and
  10. Scientific Advisory Boards:
    1. NOCIP DSMB.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. Royalties from UpToDate website for two chapters on vascular dementia.

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Merck for stroke adjudication related to a clinical trial (ongoing). Nutricia North America for one time advisory committee related to a medical food.

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. UpToDate, authorship honoraria.

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. American Heart Association SDG 0735387N

    Research Support, Government Entities:
    1. 1) NIH/NINDS K02 NS059729, PI, 2008-2013, 2) NIH/NHLBI R01 HL 108623, PI, 2012-2016, 3) NIH/NINDS R37 NS 29993, CO-I, 2008-2013, 4) NIH, subcontract from Wake Forest, PI, 2009-2018

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Mitchell S.V. Elkind, MD, MS
  12. Scientific Advisory Boards:
    1. (1) Jarvik Heart, Clinical Events Committee member, adjudicating events in clinical trial of artificial heart (2008-present)

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. (1) Neurology, Resident and Fellow Section editor, published by American Academy of Neurology (2007-present)

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. (1) Boehringer-Ingelheim, Inc., 2009-2010; (2) BMS-Sanofi Pharmaceutical Partnership, 2009-2010; (3) Genentech 2010

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1) diaDexus, Inc: funding for biomarker research; (2) BMS-Sanofi Pharmaceutical Partnership: funding for biomarker research

    Research Support, Government Entities:
    1. (1) NIH/NINDS P50 NS049060, Project PI, 2004-2013;(2) NIH/NINDS R37 NS029993, Co-PI, 2008-2013; (3) NIH/NINDS 1R25 NS070697, PI, 2010-2015

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1) American Heart Association Founders Affiliate Board of Directors)(2008-present); (2) American Heart Association NY City Board of Directors (2011-present)

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. (1) Novartis, Zelnorm and stroke litigation, 2009-2010; (2) GSK, Avandia and stroke liigation, 2009-2011; (3) Organon, NuvaRing and stroke liigation, 2009-present; (4) Boehringer-Ingelheim, Inc., Pradaxa and stroke litigation (2012)

  1. From the Department of Neurology (M.K., Y.P.M., M.S.V.E.) and Department of Epidemiology and Gertrude Sergievsky Center (M.S.V.E.), Columbia University College of Physicians and Surgeons, New York; Department of Biostatistics (M.C.P.), Mailman School of Public Health, Columbia University, New York, NY; and Departments of Neurology, Epidemiology & Public Health, and Neuroscience (R.L.S., C.B.W.), and Department of Genetics (R.L.S.), Miller School of Medicine, University of Miami, Miami, FL.
  1. Correspondence to Dr. Katan: mk3270{at}columbia.edu
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