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March 26, 2013; 80 (13) Views & Reviews

Pediatric neuroenhancement

Ethical, legal, social, and neurodevelopmental implications

William D. Graf, Saskia K. Nagel, Leon G. Epstein, Geoffrey Miller, Ruth Nass, Dan Larriviere
First published March 13, 2013, DOI: https://doi.org/10.1212/WNL.0b013e318289703b
William D. Graf
From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
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Saskia K. Nagel
From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
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Leon G. Epstein
From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
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Geoffrey Miller
From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
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Ruth Nass
From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
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Dan Larriviere
From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
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Full PDF
Citation
Pediatric neuroenhancement
Ethical, legal, social, and neurodevelopmental implications
William D. Graf, Saskia K. Nagel, Leon G. Epstein, Geoffrey Miller, Ruth Nass, Dan Larriviere
Neurology Mar 2013, 80 (13) 1251-1260; DOI: 10.1212/WNL.0b013e318289703b

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Article Information

vol. 80 no. 13 1251-1260
DOI: 
https://doi.org/10.1212/WNL.0b013e318289703b
PubMed: 
23486879

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received July 2, 2012
  • Accepted December 5, 2012
  • First Published March 13, 2013.

Article Versions

  • Previous version (March 13, 2013 - 13:02).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. William D. Graf, MD,
    2. Saskia K. Nagel, PhD,
    3. Leon G. Epstein, MD,
    4. Geoffrey Miller, MD,
    5. Ruth Nass, MD and
    6. Dan Larriviere, MD, JD
  1. William D. Graf, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. (1) Journal of Child Neurology, Editorial Board, 8 years

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Saskia K. Nagel, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. I am part of a group of four colleagues who developed a device and apply for patenting it. The process is pending. The content of the patent is not relevant to the article considered for publication here.Status Pending: The device utilizes a computing platform to record and transmit physiological signals from one person to the other.

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Research support from the Federal Ministry for Education and Research [DLR - 01GP1010], Germany. Principal Investigator, 2010-2013.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Leon G. Epstein, MD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Geoffrey Miller, MD,
  8. Scientific Advisory Boards:
    1. March of Dimes

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. Pediatric Bioethics.Cambridge University Press. 2010Extreme Prematurity.Practices, Bioethics and the law.Cambridge University Press.2007

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. Author of several entries in the internet informaationsource Up To Date

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Ruth Nass, MD and
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Dan Larriviere, MD, JD
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. American Association for the Advancement of Science, speaker honorarium

    Editorial Boards:
    1. Neurology Today, editorial advisory board 2010-currentContinuum Audio, Associate Editor

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Ochsner Health System

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Departments of Pediatrics and Neurology (W.D.G., G.M.), Yale University, New Haven, CT; Institute of Cognitive Science (S.K.N.), University of Osnabrück, Osnabrück Germany; Department of Pediatrics (L.G.E.), Northwestern University's Feinberg School of Medicine, Chicago, IL; Departments of Neurology, Child & Adolescent Psychiatry, and Pediatrics (R.N.), New York University Langone Medical Center, New York; and Department of Neurology (D.L.), Ochsner Medical Center, New Orleans, LA.
  1. Correspondence to Dr. Graf: william.graf{at}yale.edu
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Cited By...

  • 41 Citations
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Disputes & Debates: Rapid online correspondence

  • Pediatric Neuroenhancment
    • Steven M. Rothman, Pediatric Neurologist, Mercy Clinic St Louissrothman62@gmail.com
    Submitted April 16, 2013
  • Reply to Rothman
    • William D. Graf, Child Neurologist, Yale School of Medicinewilliam.graf@yale.edu
    • William D. Graf, New Haven, CT; Saskia K. Nagel, Osnabr?ck Germany; Leon G. Epstein, Chicago, IL; Geoffrey Miller, New Haven, CT; Dan Larriviere, New Orleans, LA
    Submitted April 16, 2013
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  • Article
    • Abstract
    • GLOSSARY
    • METHODS
    • PEDIATRIC NEUROENHANCEMENT AND EMERGING PRACTICE TRENDS
    • ETHICAL DECISION-MAKING PRINCIPLES FOR NEUROENHANCEMENT IN PEDIATRIC POPULATIONS
    • DEVELOPMENTAL ISSUES RELEVANT TO NEUROENHANCEMENT
    • SOCIAL AND LEGAL ISSUES RELEVANT TO NEUROENHANCEMENT
    • PROFESSIONAL ISSUES RELEVANT TO NEUROENHANCEMENT
    • DISCUSSION
    • AUTHOR CONTRIBUTIONS
    • STUDY FUNDING
    • DISCLOSURE
    • APPENDIX
    • ACKNOWLEDGMENT
    • Footnotes
    • REFERENCES
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