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May 21, 2013; 80 (21) NeuroImages

Midbrain neurocysticercal granuloma appearing as “face of panda”

Ramesh Konanki, Dandu Ravi Varma, Lokesh Lingappa, Bhamy Hariprasad Shenoy
First published May 20, 2013, DOI: https://doi.org/10.1212/WNL.0b013e318293e357
Ramesh Konanki
From Rainbow Children's Hospital and Perinatal Centre (R.K., L.L.); Care Hospitals (D.R.V.); and LV Prasad Eye Institute (B.H.P.S.), Hyderabad, India.
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Dandu Ravi Varma
From Rainbow Children's Hospital and Perinatal Centre (R.K., L.L.); Care Hospitals (D.R.V.); and LV Prasad Eye Institute (B.H.P.S.), Hyderabad, India.
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Lokesh Lingappa
From Rainbow Children's Hospital and Perinatal Centre (R.K., L.L.); Care Hospitals (D.R.V.); and LV Prasad Eye Institute (B.H.P.S.), Hyderabad, India.
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Bhamy Hariprasad Shenoy
From Rainbow Children's Hospital and Perinatal Centre (R.K., L.L.); Care Hospitals (D.R.V.); and LV Prasad Eye Institute (B.H.P.S.), Hyderabad, India.
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Midbrain neurocysticercal granuloma appearing as “face of panda”
Ramesh Konanki, Dandu Ravi Varma, Lokesh Lingappa, Bhamy Hariprasad Shenoy
Neurology May 2013, 80 (21) 1999; DOI: 10.1212/WNL.0b013e318293e357

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An 8-year-old girl presented with a 5-day history of double vision on attempting to look downward. Examination of her eye movements revealed weakness of bilateral superior oblique muscles, with a normal examination otherwise. The brain MRI revealed a cysticercal granuloma of the midbrain ventral to the cerebral aqueduct with perilesional edema, sparing both red nuclei, and giving the appearance of “face of panda” (figure, A and B). The face of panda sign has been described in cases of Wilson disease, including “face of giant panda” and “face of panda cub” in the midbrain and pons, respectively.1,2

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Figure Midbrain “face of panda” due to neurocysticercal granuloma

Axial fluid-attenuated inversion recovery (A) and T2-weighted (B) MRI of midbrain reveal a cyst with mural nodule, in the periaqueductal grey matter, ventral to the aqueduct. Edema involving the surrounding white matter, sparing the red nuclei and cerebral peduncles, is seen.

Footnotes

  • Author contributions: R.K., L.L., and B.H.S. provided clinical care to the patient and drafted the manuscript. D.R.V. provided radiologic input.

  • Study funding: No targeted funding reported.

  • Disclosures: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.

  • © 2013 American Academy of Neurology

References

  1. 1.↵
    1. Hitoshi S,
    2. Iwata M,
    3. Yoshikawa K
    . Mid-brain pathology of Wilson's disease: MRI analysis of three cases. J Neurol Neurosurg Psychiatry 1991;54:624–626.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    1. Shivakumar R,
    2. Thomas SV
    . Face of the giant panda and her cub: MRI correlates of Wilson disease. Neurology 2009;72;e50.
    OpenUrlFREE Full Text

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