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Apart from the iatrogenic effects of treatment, neurologic complications of Hodgkin lymphoma (HL) can be divided into direct (meningeal or intracranial/spinal localization) and indirect (paraneoplastic/immune complications).1 Here, we present a patient with granulomatous angiitis of the CNS (GANS) associated with HL that dramatically improved after the treatment of the angiitis by cyclophosphamide, methylprednisolone, and specific chemotherapy.
Footnotes
Study funding: No targeted funding reported.
Supplemental data at www.neurology.org
Author contributions: Loïc Le Guennec, Damien Roos-Weil, and Nicolas Weiss wrote the manuscript. Karima Mokhtari and Dimitri Psimaras performed the anatomopathologic study and critically reviewed its results. Dorian Chauvet, Peggy Reiner, Sophie Demeret, Sylvain Choquet, and Francis Bolgert critically reviewed the manuscript.
Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.
- Received April 20, 2012.
- Accepted September 21, 2012.
- © 2012 American Academy of Neurology
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Letters: Rapid online correspondence
- Granulomatous Angiitis of the CNS Revealing a Hodgkin Lymphoma, No Evidence for Varicella Zoster Virus Infection
- Granulomatous Angiitis of the CNS, Hodgkin Lymphoma and the Herpes Zoster Virus
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