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February 12, 2013; 80 (7) Article

Prognostic factors of motor impairment, disability, and quality of life in newly diagnosed PD

Daan C. Velseboer, Mark Broeders, Bart Post, Nan van Geloven, Johannes D. Speelman, Ben Schmand, Rob J. de Haan, Rob M.A. de Bie, on behalf of the CARPA Study Group
First published January 23, 2013, DOI: https://doi.org/10.1212/WNL.0b013e318281cc99
Daan C. Velseboer
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Mark Broeders
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Bart Post
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Nan van Geloven
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Johannes D. Speelman
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Ben Schmand
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Rob J. de Haan
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Rob M.A. de Bie
From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
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Prognostic factors of motor impairment, disability, and quality of life in newly diagnosed PD
Daan C. Velseboer, Mark Broeders, Bart Post, Nan van Geloven, Johannes D. Speelman, Ben Schmand, Rob J. de Haan, Rob M.A. de Bie, on behalf of the CARPA Study Group
Neurology Feb 2013, 80 (7) 627-633; DOI: 10.1212/WNL.0b013e318281cc99

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Article Information

vol. 80 no. 7 627-633
DOI: 
https://doi.org/10.1212/WNL.0b013e318281cc99
PubMed: 
23345637

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received June 13, 2012
  • Accepted October 11, 2012
  • First Published January 23, 2013.

Article Versions

  • Previous version (January 23, 2013 - 13:01).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. Daan C. Velseboer, MD,
    2. Mark Broeders, MSc,
    3. Bart Post, MD, PhD,
    4. Nan van Geloven, MSc,
    5. Johannes D. Speelman, MD, PhD,
    6. Ben Schmand, PhD,
    7. Rob J. de Haan, PhD,
    8. Rob M.A. de Bie, MD, PhD;
    9. on behalf of the CARPA Study Group
  1. Daan C. Velseboer, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Mark Broeders, MSc,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Bart Post, MD, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Nan van Geloven, MSc,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Johannes D. Speelman, MD, PhD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. 1. Medtronic ltd, Minneapolis, concerning DBS

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. 1. Medtronic Ltd Minneapolis

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Ben Schmand, PhD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. Abbott, partial funding for travel and conference attendance.

    Editorial Boards:
    1. Tijdschrift voor Neuropsychologie, 2005 - present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Michael J. Fox Foundation

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Rob J. de Haan, PhD,
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Rob M.A. de Bie, MD, PhD;
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. Received funding for a trip from Medtronic (2010) and fora trip from Abbot (2010).

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Received an unrestricted fellowship grant from Medtronic.Received a reserach grant from GE Health

    Research Support, Government Entities:
    1. Received a research grant from ZonMw Doelmatigheid(171102018).

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Received research grants from the Parkinson Vereniging(Patient's Society), the Prinses Beatrix Fonds (WAR08-02), Internationaal Parkinson Fonds, Michael J FoxFoundation, Kinetics Foundation

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  17. on behalf of the CARPA Study Group
  1. From the Department of Neurology (D.C.V., J.D.S., B.S., R.M.A.d.B.), Clinical Research Unit (N.v.G., R.J.d.H.), Academic Medical Center, and Department of Brain and Cognition (M.B., B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
  1. Correspondence to Dr. Velseboer: d.c.velseboer{at}amc.uva.nl
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