Sweetened-Beverages, Coffee, and Tea in Relation to Depression among Older US Adults (P05.122)
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Abstract
OBJECTIVE: To prospectively evaluate consumptions of sweetened-beverages, coffee and tea in relation to depression among older US adults.
BACKGROUND: Sweetened-beverages, coffee and tea are commonly consumed worldwide and have important physical and mental health consequences.
DESIGN/METHODS: We prospectively evaluated consumptions of these beverages, in relation to depression among 263,925 older US adults. Beverage consumptions were assessed in 1995-1996, and 11,311 depression diagnoses since 2000 were self-reported in 2004-2006. Odds ratios (OR) and 95% confidence intervals (CI) were derived from multivariate logistic regressions.
RESULTS: Drinking sweetened-beverages was associated with higher depression risk, whereas coffee drinking was weakly related to lower risk. The OR and 95%CI comparing ≥4 cans/cups per day with none were 1.30 (1.17–1.44) for soft drinks, 1.38 (1.15-1.65) for fruit punches, and 0.91 (0.84-0.98) for coffee (all P for trend < 0.0001). Further analysis seemed to suggest stronger associations with diet drinks than with regular. The ORs between extreme categories were 1.31 (1.16-1.47) for diet versus 1.22 (1.03-1.45) for regular soft drinks, 1.51 (1.18-1.92) for diet versus 1.08 (0.79-1.46) for regular fruit punches, and 1.25 (1.10-1.41) for diet versus 0.94 (0.83-1.08) for regular iced tea. Consistently, constituent-based analyses showed higher depression risk with aspartame intake [ORs between extreme quintiles: 1.36 (1.29-1.44)], and lower risk with caffeine intake [corresponding OR 0.83 (0.78-0.89)].
CONCLUSIONS: This large prospective study suggests that frequent consumption of diet sweetened-beverages may increase depression risk among older adults, whereas coffee consumption may lower the risk.
Supported by: Intramural Research Programs of NIH,the National Institute of Environmental Health Sciences and the National Cancer Institute.
Disclosure: Dr. Chen has nothing to disclose. Dr. Guo has received personal compensation for activities with Westat, Inc. as an employee. Dr. Park has nothing to disclose. Dr. Freedman has nothing to disclose. Dr. Shinha has nothing to disclose. Dr. Hollenbeck has nothing to disclose. Dr. Blair has nothing to disclose.
Wednesday, March 20 2013, 2:00 pm-7:00 pm
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