Skip to main content
Advertisement
  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Education
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Online Sections
    • Neurology Video Journal Club
    • Diversity, Equity, & Inclusion (DEI)
    • Neurology: Clinical Practice Accelerator
    • Practice Buzz
    • Practice Current
    • Residents & Fellows
    • Without Borders
  • Collections
    • COVID-19
    • Disputes & Debates
    • Health Disparities
    • Infographics
    • Neurology Future Forecasting Series
    • Null Hypothesis
    • Patient Pages
    • Topics A-Z
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit New Manuscript
    • Submit Revised Manuscript
    • Author Center

Advanced Search

Main menu

  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Education
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Online Sections
    • Neurology Video Journal Club
    • Diversity, Equity, & Inclusion (DEI)
    • Neurology: Clinical Practice Accelerator
    • Practice Buzz
    • Practice Current
    • Residents & Fellows
    • Without Borders
  • Collections
    • COVID-19
    • Disputes & Debates
    • Health Disparities
    • Infographics
    • Neurology Future Forecasting Series
    • Null Hypothesis
    • Patient Pages
    • Topics A-Z
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit New Manuscript
    • Submit Revised Manuscript
    • Author Center
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Neurology Video Journal Club
  • Residents & Fellows

User menu

  • Subscribe
  • My Alerts
  • Log in

Search

  • Advanced search
Neurology
Home
The most widely read and highly cited peer-reviewed neurology journal
  • Subscribe
  • My Alerts
  • Log in
Site Logo
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Neurology Video Journal Club
  • Residents & Fellows

Share

February 12, 2013; 80 (7 Supplement) March 20,2013

Admission Blood Glucose Predicts High Hematoma Volume in Intracerebral Hemorrhage (P05.229)

Carrie Kubiak, Wazim Mohamed, Pratik Bhattacharya
First published February 8, 2016,
Carrie Kubiak
1 Wayne State University School of Medicine Detroit MI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wazim Mohamed
2 Wayne State University School of Medicine Detroit MI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pratik Bhattacharya
3 Wayne State University School of Medicine Saint Clair Shores MI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Citation
Admission Blood Glucose Predicts High Hematoma Volume in Intracerebral Hemorrhage (P05.229)
Carrie Kubiak, Wazim Mohamed, Pratik Bhattacharya
Neurology Feb 2013, 80 (7 Supplement) P05.229;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Permissions

Make Comment

See Comments

Downloads
0

Share

  • Article
  • Info & Disclosures
Loading

Abstract

OBJECTIVE: To assess the effect of admission blood glucose on hematoma volume in intracerebral hemorrhage (ICH).

BACKGROUND: Admission blood glucose (BG) is a predictor of poor outcome in patients with ICH. We tested the hypothesis that this may be due to an effect on hematoma volume (presumably from transient endothelial dysfunction).

DESIGN/METHODS: Records of patients with primary ICH from a community hospital and two teaching hospitals over 36 months were reviewed. Traumatic and subarachnoid hemorrhages were excluded. Patient demographics, history of diabetes, BG and modified rankin scale (mRS) at discharge were calculated. An mRS of 0- 2 was defined as good outcome and 3-6 was considered a poor outcome. Hematoma volume was calculated on the admission CT by using the formula of ABC/2.

RESULTS: The analysis included 168 patients (mean age 62±13 years;51.8% males). Of the patients, 23.8% had a prior history of diabetes and 33.9% presented with an admission BG>140 mg/dl. The mean ICH volume among patients with BG>140 mg/dl was 65±76.3 cm3 vs. 21.6±27.9 cm3 in those with BG<140 mg/dl (p<0.0010). A history of diabetes did not correlate with hematoma volume (p=0.19). Among those with a BG>140 mg/dl, 84.5% had a bad outcome compared to 63.6 % among those with BG<140 (p=0.004).In a logistic regression model patients with BG>140 mg/dl were three times more likely to have a poor outcome at discharge (OR 3.1;CI 1.4–6.9). Upon correcting for hematoma volume, admission blood glucose no longer correlated with discharge outcome (p=0.3), suggesting that the effect of high BG on outcome may be due to increased hematoma volumes.

CONCLUSIONS: Acute elevation of blood glucose rather than a history of diabetes predicts higher hematoma volumes in ICH. Transient endothelial dysfunction needs to be evaluated as a potential mechanism mediating this association. Further analysis to study whether blood glucose control prevents hematoma expansion is warranted.

Disclosure: Dr. Kubiak has nothing to disclose. Dr. Mohamed has nothing to disclose. Dr. Bhattacharya has nothing to disclose.

Wednesday, March 20 2013, 2:00 pm-7:00 pm

  • Copyright © 2013 by AAN Enterprises, Inc.

Letters: Rapid online correspondence

No comments have been published for this article.
Comment

REQUIREMENTS

You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.

Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.

If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.

Submission specifications:

  • Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
  • Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
  • Submit only on articles published within 6 months of issue date.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Publishing Agreement Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top
  • Article
  • Info & Disclosures
Advertisement

Safety and Efficacy of Tenecteplase and Alteplase in Patients With Tandem Lesion Stroke: A Post Hoc Analysis of the EXTEND-IA TNK Trials

Dr. Nicole Sur and Dr. Mausaminben Hathidara

► Watch

Related Articles

  • No related articles found.

Alert Me

  • Alert me when eletters are published
Neurology: 100 (22)

Articles

  • Ahead of Print
  • Current Issue
  • Past Issues
  • Popular Articles
  • Translations

About

  • About the Journals
  • Ethics Policies
  • Editors & Editorial Board
  • Contact Us
  • Advertise

Submit

  • Author Center
  • Submit a Manuscript
  • Information for Reviewers
  • AAN Guidelines
  • Permissions

Subscribers

  • Subscribe
  • Activate a Subscription
  • Sign up for eAlerts
  • RSS Feed
Site Logo
  • Visit neurology Template on Facebook
  • Follow neurology Template on Twitter
  • Visit Neurology on YouTube
  • Neurology
  • Neurology: Clinical Practice
  • Neurology: Education
  • Neurology: Genetics
  • Neurology: Neuroimmunology & Neuroinflammation
  • AAN.com
  • AANnews
  • Continuum
  • Brain & Life
  • Neurology Today

Wolters Kluwer Logo

Neurology | Print ISSN:0028-3878
Online ISSN:1526-632X

© 2023 American Academy of Neurology

  • Privacy Policy
  • Feedback
  • Advertise