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October 01, 2013; 81 (14) Views & Reviews

Migraine and structural changes in the brain

A systematic review and meta-analysis

Asma Bashir, Richard B. Lipton, Sait Ashina, Messoud Ashina
First published August 28, 2013, DOI: https://doi.org/10.1212/WNL.0b013e3182a6cb32
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Article Information

vol. 81 no. 14 1260-1268
DOI: 
https://doi.org/10.1212/WNL.0b013e3182a6cb32
PubMed: 
23986301
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received January 9, 2013
  • Accepted in final form July 1, 2013
  • First Published August 28, 2013.

Article Versions

Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. Asma Bashir, MD,
    2. Richard B. Lipton, MD,
    3. Sait Ashina, MD and
    4. Messoud Ashina, MD, PhD
  1. Asma Bashir, MD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Richard B. Lipton, MD,
    3. Scientific Advisory Boards:

    1. Allergan, e-Neura, Merck

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. American Headache Society, Cognimed, Diamond Headache Clinic Research, Market Force Communications, Merck, Talley Management

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. Oxford University Press; Baxter Publishing

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. Allergan, Autonomic Technologies, Boston Scientific, CoLucid, GlaxoSmithKline,Novartis, NuPathe

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Bristol Myers Squibb Eaarly Detection of Alzheimer's Disease June 2010 - present Vedanta Research Migraine epidemiology and Progression June 2010 - present Boston Scientific Occipital Nerve Stimulation in Migraine March 2013 - present ElectroCore Vagal Nerve Stimulation for Migraine and Cluster May 2013 Novartis Sleep and Migraine September 2012 - present Allergan Botox in Migraine April 2012 - present Allergan Chronic Migraine Epidemiology and Outcome Study January 2012 - present

    Research Support, Government Entities:

    1. P01 AG03949 4/1/11-3/31/16 Einstein Aging Study Role: Principle Investigator 1KL2RR025749 07/01/09-06/30/13 Clinical and Translational Science Award (CTSA) Research Career Development Award Role: Primary Mentor R01AG022374 8/1/10-7/31/15 Biomarkers in Early Alzheimer's Disease Role: Investigator R01AG034119 8/1/10-7/31/15 Two Preclinical Latent Scores to Predict Occurrence of DAT Role: PI, Einstein Site R01AG012101 9/15/10-7/31/15 MRI Progression Markers of Cognitive Decline in the Elderly Role: PI, Einstein Site 1R01AG039409-01 Stress, Unconstructive Repetitive Thought & Cognitive Aging 4/1/11-3/31/16 Role: PI, Einstein Site 1R01AG038651-01A1 Role of impaired cognitive states & risk factors in conversion to mixed dementias 9/1/11-8/31/16 Role: PI, Einstein Site 1U10NS077308- 01 9/30/11-8/31/18 Einstein Center for Excellence for Clinical Trials in Neuroscience Role: PI NIH 4/1/12-3/31/17 Behavioral Weight Loss as a Treatment for Migraine in Obese Women Role: Investigator NIH 1R01AG042595 - 01A1 Stress, cognition, repetitive unconstructive thoughts and inflammatory markers Role: Investigator

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. S & L Marx Foundation Alzheimer's Research

    Stock/Stock Options/Board of Directors Compensation:

    1. Minster Pharma

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Sait Ashina, MD and
    4. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. speaker honoraria from Allergan and NeurogesX

    Editorial Boards:

    1. 1. Visiting Associate Editor, Journal of Headache and Pain 2012-now 2. Associate Editor, Neurology Reviews, 2010-now

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. Assistant Professor of Neurology and Anesthesiology, Beth Israel Medical Center, Albert Einstein College of Medicine

    Consultancies:

    1. Have served as a consultant on advisory board of Depomed

    Speakers' Bureaus:

    1. On speakers bureau for Allergan and Nautilus Neurosciences

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. Messoud Ashina, MD, PhD
    5. Scientific Advisory Boards:

    1. Dr. Ashina is a consultant and/or scientific adviser for the ATI, Allergan, Amgen and Alder.

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. 2009: Dr. Messoud Ashina has received support from Merck to participate at the International Headache Society Congress

    Editorial Boards:

    1. Massoud Ashina is an associate editor of Cephalgia Member of advisory board: The Journal of Headache and Pain

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. Honoraria for lecturing from Pfizer, GlaxoSmithKline, Norpharma, AstraZeneca and Allergans

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Danish Headache Center and Department of Neurology (A.B., M.A.), Glostrup Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Glostrup, Copenhagen, Denmark; Montefiore Headache Center (R.B.L.), Department of Neurology, Albert Einstein College of Medicine, Bronx; and Headache Program (S.A.), Department of Pain Medicine and Palliative Care, Department of Neurology, Albert Einstein College of Medicine, Beth Israel Medical Center, New York, NY.
  1. Correspondence to Dr. M. Ashina: ashina{at}dadlnet.dk
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