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Autoimmune encephalitides are a group of heterogeneous disorders1 whose clinical phenotypes and association with specific neuronal surface receptors and synaptic proteins have been described in an interval of less than a decade since the first reports of the prototypical autoimmune encephalitis associated with NMDA receptor (NMDAR) antibodies.2 There has been a remarkable explosion of both basic science and clinical observations to establish this group of disorders as treatable autoimmune neurologic disorders. The potential for successful treatment and even remission of these disorders makes recognition of them critical for practicing neurologists, as the prognosis is better with early, aggressive immunotherapy.
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- © 2013 American Academy of Neurology
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