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December 10, 2013; 81 (24) Article

An RCT to treat learning impairment in multiple sclerosis

The MEMREHAB trial

Nancy D. Chiaravalloti, Nancy B. Moore, Olga M. Nikelshpur, John DeLuca
First published November 8, 2013, DOI: https://doi.org/10.1212/01.wnl.0000437295.97946.a8
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Article Information

vol. 81 no. 24 2066-2072
DOI: 
https://doi.org/10.1212/01.wnl.0000437295.97946.a8
PubMed: 
24212393
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received January 22, 2013
  • Accepted in final form August 12, 2013
  • First Published November 8, 2013.

Article Versions

Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. Nancy D. Chiaravalloti, PhD,
    2. Nancy B. Moore, MA,
    3. Olga M. Nikelshpur, PhD and
    4. John DeLuca, PhD
  1. Nancy D. Chiaravalloti, PhD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. Brain Changes, Changes in Daily LifeSpringerin preparation

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. Title of Project: Improving New Learning and Memory in TBI: Applying fMRI to Measure OutcomeFunding Agency: National Institute on Disability and Rehabilitation Research (NIDRR)Role: Principal Investigator Type of Award: Field Initiated GrantDates: 10/1/09 – 9/30/12Award Number: H133A070037Title of Project: Advanced Rehabilitation Research Training (AART) Center on Neurocognitive RehabilitationFunding Agency: National Institute on Disability and Rehabilitation Research (NIDRR)Role: Project DirectorType of Award: Fellowship Training GrantDates: 7/1/2009 - 6/30-2014 Award Number: H133P090009Title of Project: Improving Learning in TBI: A Randomized Clinical Trial Funding Agency: National Institute on Disability and Rehabilitation Research (NIDRR)Role: Principal Investigator Type of Award: Major site specific project in the TBI Model Systems GrantDates: 10/1/07 – 9/30/12Award Number: H133A070037Title of Project: Competitive Supplement to Improving Learning in MS: A Randomized Clinical TrialFunding Agency National Institutes of Health (NCMRR)Role: Principal InvestigatorType of Award: Competitive Supplement to ongoing RO1 Dates: 5/1/07 – 4/30/11 Title of Project: Improving Learning in MS: A Randomized Clinical Trial Funding Agency National Institutes of Health (NCMRR)Role: Principal InvestigatorType of Award: R01 Dates: 7/1/04 – 4/30/11

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Nancy B. Moore, MA,
    3. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Olga M. Nikelshpur, PhD and
    4. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. John DeLuca, PhD
    5. Scientific Advisory Boards:

    1. (1) William Paterson University, Scientific Advisory Board, 2001-Present(2) Board of Directors, Division 22 Rehabilitation Psychology, American Psychological Association, Member at Large, 2010 - 2013(3) Board of Directors, National Academy of Neurology, Member at Large, 2010 - 2012(4) Board of Trustees, New Jersey Neuropsycholocial Society, 1997 - present

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. (1) National Multiple Sclerosis Society, Travel Expenses for an invited talk for the ISPMSC Conference in Milan, Italy, February 2013(2) Case University travel expenses and honoraria for presenting Grand Rounds, April 2013(3) Consortium of Multiple Sclerosis Centers, travel expenses for invited talk, April 2013 and May 2013(4) DIH Technologies, travel expenses for invited talk at the ISPRM conference in China, June 2013(5) IMSCOGS Conference, travel expenses for invited talk at its 2013 conference, June 2013

    Editorial Boards:

    1. (1) Journal of Clinical and Experimental, Board, 2009-present(2) Rehabilitation Psychology, Board, 1999-present(3) Neuro-Psychoanalysis, Board, 1999-present(4) Neuropsychology Review, Board, 2005-present(5) Archives of Physical Medicine and Rehabilitation, Associate Editor, 2005-present(6) Multiple Sclerosis, Board, 2006-present

    Patents:

    1. NONE

    Publishing Royalties:

    1. (1) Encyclopedia of Clinical Neurpsychology, Springer, 2011(2) Handbook for the Assessment of Driving Capacity, Elsevier, 2009(3) Information Processing Speed in Clinical Populations, Taylor & Francis Group, 2008(4) Functional Neuroimaging in Clinical Populations, The Guilford Press, 2007(5) Fatigue as a Window to the Brain, The MIT Press, 2005

    Employment, Commercial Entity:

    1. (1) Kessler Foundation, Vice President for Research

    Consultancies:

    1. (1) Biogen Idec(2) Memen Pharmaceuticals

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. (1) Biogen Idec(2) Memen Pharmaceuticals

    Research Support, Government Entities:

    1. (1) National Multiple Sclerosis Society, MB0024Principal Investigator(2) National Multiple Sclerosis Society, RG4232A1/1, Co-Investigator(3) National Institute on Disability and Rehabilitation Research, H133A070037, Co-Investigator(4) National Institutes of Health, NCMRR, RO1HD045798, Co-Investigator

    Research Support, Academic Entities:

    1. (1) Rutgers New Jersey School of Medicine - Professor, Departments of Physical Medicine and Rehabilitation and Neurology and Neurosciences(2)Touro College, New York, Clinical Professor of Psychology

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Kessler Foundation Neuropsychology and Neuroscience Laboratory (N.D.C., N.B.M., O.M.N., J.D.), West Orange; and Departments of Physical Medicine and Rehabilitation (N.D.C., O.M.N., J.D.) and Neurology & Neurosciences (J.D.), Rutgers, New Jersey Medical School, Newark, NJ.
  1. Correspondence to Dr. Chiaravalloti: nchiaravalloti{at}kesslerfoundation.org
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