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July 23, 2013; 81 (4) Article

Inverse occurrence of cancer and Alzheimer disease

A population-based incidence study

Massimo Musicco, Fulvio Adorni, Simona Di Santo, Federica Prinelli, Carla Pettenati, Carlo Caltagirone, Katie Palmer, Antonio Russo
First published July 10, 2013, DOI: https://doi.org/10.1212/WNL.0b013e31829c5ec1
Massimo Musicco
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Fulvio Adorni
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Simona Di Santo
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Federica Prinelli
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Carla Pettenati
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Carlo Caltagirone
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Katie Palmer
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Antonio Russo
From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
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Full PDF
Citation
Inverse occurrence of cancer and Alzheimer disease
A population-based incidence study
Massimo Musicco, Fulvio Adorni, Simona Di Santo, Federica Prinelli, Carla Pettenati, Carlo Caltagirone, Katie Palmer, Antonio Russo
Neurology Jul 2013, 81 (4) 322-328; DOI: 10.1212/WNL.0b013e31829c5ec1

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Article Information

vol. 81 no. 4 322-328
DOI: 
https://doi.org/10.1212/WNL.0b013e31829c5ec1
PubMed: 
23843468

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received January 29, 2013
  • Accepted in final form March 27, 2013
  • First Published July 10, 2013.

Article Versions

  • Previous version (July 10, 2013 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. Massimo Musicco, MD,
    2. Fulvio Adorni, PhD,
    3. Simona Di Santo, MSc,
    4. Federica Prinelli, MSc,
    5. Carla Pettenati, MD,
    6. Carlo Caltagirone, MD,
    7. Katie Palmer, PhD and
    8. Antonio Russo, MD
  1. Massimo Musicco, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. 1) In the last 3 years I received an unconditioned research grant from Abbott Italy for a multi center research on RSV infections in children. 2) In the last two years I received an unconditioned research grant from Novartis for a multi center research on Goal Attainment Scale in patients with Alzheimer's disease. These grants were ruled by specific contracts with my Institution (National Research Council of Italy)

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Fulvio Adorni, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Simona Di Santo, MSc,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. “The Journal of Alzheimer's Disease”, associate editor, 2013. (no compensation) “Yonsei Medical Journal”, referee, 2013. (no compensation)

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Federica Prinelli, MSc,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Carla Pettenati, MD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. honoraria from Lundbeck for teaching course

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Carlo Caltagirone, MD,
  12. Scientific Advisory Boards:
    1. From Lilly, as a member of the Scientific Advisory Board in 2011-2012, from Novartis, as a member of the Scientific Advisory Board, in 2011-2012.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Italian Ministry of Health RF97, year 2011-2012

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Katie Palmer, PhD and
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Antonio Russo, MD
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) Lombardy Regional Authority, Cancer Registry, Principal Investigator, 2011, 2012 (2) Lombardy Regional Authority, Oncologic Indicators, Principal Investigator, 2011, 2012

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the National Research Council of Italy (M.M., F.A., F.P.), Institute of Biomedical Technologies, Segrate (Milan); Foundation IRCCS “Santa Lucia” (M.M., S.D., C.C., K.P.), Rome; Alzheimer Departmental Unit (C.P.), AO of Garbagnate (Milan); University “Tor Vergata” (C.C.), Rome; and Epidemiology Unit (A.R.), Local Health Authority of Milano 1, Milan, Italy.
  1. Correspondence to Dr. Musicco: massimo.musicco{at}itb.cnr.it
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