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August 20, 2013; 81 (8) Article

Early seizure onset and dysplastic lesion extent independently disrupt cognitive networks

Brandon Korman, Pavel Krsek, Michael Duchowny, Bruno Maton, Esperanza Pacheco-Jacome, Gustavo Rey
First published July 19, 2013, DOI: https://doi.org/10.1212/WNL.0b013e3182a1aa2a
Brandon Korman
From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
PsyD
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Pavel Krsek
From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
MD, PhD
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Michael Duchowny
From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
MD
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Bruno Maton
From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
MD
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Esperanza Pacheco-Jacome
From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
MD
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Gustavo Rey
From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
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Full PDF
Citation
Early seizure onset and dysplastic lesion extent independently disrupt cognitive networks
Brandon Korman, Pavel Krsek, Michael Duchowny, Bruno Maton, Esperanza Pacheco-Jacome, Gustavo Rey
Neurology Aug 2013, 81 (8) 745-751; DOI: 10.1212/WNL.0b013e3182a1aa2a

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Article Information

vol. 81 no. 8 745-751
DOI: 
https://doi.org/10.1212/WNL.0b013e3182a1aa2a
PubMed: 
23873975

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received October 26, 2012
  • Accepted in final form May 10, 2013
  • First Published July 19, 2013.

Article Versions

  • Previous version (July 19, 2013 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2013 American Academy of Neurology

Author Disclosures

    1. Brandon Korman, PsyD,
    2. Pavel Krsek, MD, PhD,
    3. Michael Duchowny, MD,
    4. Bruno Maton, MD,
    5. Esperanza Pacheco-Jacome, MD and
    6. Gustavo Rey, PhD
  1. Brandon Korman, PsyD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Miami Children's Hospital, Neuropsychologist

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. U. S. Army Medical Research and Materiel Command, W81XWH- 06-1-0663, 2006-Present, Sub-investigator

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Pavel Krsek, MD, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Michael Duchowny, MD,
  6. Scientific Advisory Boards:
    1. (1) Questcor Pharmaceutical, sceintific advisor, 2010

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Ortho-McNeil Pharmaceutical, scientific presentation, 2009

    Editorial Boards:
    1. Journal of Child Neurology, Associate Editor, 1997-present Epilepsia, Associate Editor, 2006-present Faculty of 100 Medicine, Section Editor, 2004-present Pediatric Neurology, Editor, 1997-present Epileptic Disorders, Editor, 1998-present Epilepsy Research and Treatment, Editor, 2009-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. Intractable Focal Epilepsy, WB Saunders, 2000 Pediatric Epilepsy, McGraw-Hill, 2013

    Employment, Commercial Entity:
    1. GSK Pharmaceuticals, speaking engagement, 2009

    Consultancies:
    1. Guidepoint Global, consultant, 2009-2010

    Speakers' Bureaus:
    1. UCB Pharmaceuticals, 2009-2010 GSK Pharmaceuticals, 2009-2010

    Other activities:
    1. Consulatant, The Israel Institute for Medical Assistance, 2009

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Neuropace, 2009-2010 Novartis, 2009-2010 King Pharmaceuticals,2010

    Research Support, Government Entities:
    1. Department of Defense, USAMRAA Grant No. 05098002; Contract No. XWH-06-1-0663, 2007-present

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Bruno Maton, MD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Esperanza Pacheco-Jacome, MD and
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Miami Children Hospital Neuroradiologist

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Gustavo Rey, PhD
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Miami Children's Hospital Clinical Neuropsychologist

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. W81XWH-06-1-0663 Ragheb (PI) 7/2006-Present U. S. Army Medical Research and Materiel Command Traumatic Brain Injury: Multimodal Biomarker Screening Role: Sub-investigator

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Brain Institute (B.K., M.D., G.R.) and Division of Radiology (E.P.-J.), Miami Children's Hospital, FL; Department of Pediatric Neurology (P.K.), Charles University, Prague, Czech Republic; and Division of Neurology (B.M.), Sentara Heart Hospital, Norfolk, VA.
  1. Correspondence to Dr. Korman: bkorman{at}mch.com

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