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January 21, 2014; 82 (3) ArticleOpen Access

Herpes zoster as a risk factor for stroke and TIA

A retrospective cohort study in the UK

Judith Breuer, Maud Pacou, Aline Gauthier, Martin M. Brown
First published January 2, 2014, DOI: https://doi.org/10.1212/WNL.0000000000000038
Judith Breuer
From the Division of Infection and Immunity (J.B.), and Institute of Neurology (M.M.B.), University College London; and Amaris (M.P., A.G.).
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Maud Pacou
From the Division of Infection and Immunity (J.B.), and Institute of Neurology (M.M.B.), University College London; and Amaris (M.P., A.G.).
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Aline Gauthier
From the Division of Infection and Immunity (J.B.), and Institute of Neurology (M.M.B.), University College London; and Amaris (M.P., A.G.).
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Martin M. Brown
From the Division of Infection and Immunity (J.B.), and Institute of Neurology (M.M.B.), University College London; and Amaris (M.P., A.G.).
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Citation
Herpes zoster as a risk factor for stroke and TIA
A retrospective cohort study in the UK
Judith Breuer, Maud Pacou, Aline Gauthier, Martin M. Brown
Neurology Jan 2014, 82 (3) 206-212; DOI: 10.1212/WNL.0000000000000038

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This article has corrections. Please see:

  • Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK - June 17, 2014
  • EDITORIAL EXPRESSION OF CONCERN: Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK - February 05, 2014
  • Herpes zoster as a risk factor for stroke and TIA - July 08, 2014
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    Figure 1 Kaplan-Meier curves for the risk of stroke, TIA, and MI over the study follow-up period

    The time to stroke (A) after the index date does not differ significantly for cases of herpes zoster and matched controls, but is significantly shorter for TIA (B) and myocardial infarction (MI) (C) in cases compared with controls.

  • Figure 2
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    Figure 2 Adjusted risk (hazard ratio and 95% confidence interval) of stroke, TIA, and MI by age group at index date

    Risk of (A) stroke, (B) TIA, and (C) myocardial infarction (MI) by decade. (D) Time to stroke in cases and controls younger than 40 years. Hazard ratios adjusted for vascular risk factors for stroke, TIA, and MI are significantly higher for cases of herpes zoster occurring before 40 years of age compared with matched controls.

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    Four tables and one figure; two Microsoft Word files.

    Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
    © 2014 American Academy of Neurology.

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    • Tables e-1 to e-4 - Microsoft Word file
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  • Expression of Concern

    Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
    © 2014 American Academy of Neurology.

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  • Abstract in Arabic

    Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
    © 2014 American Academy of Neurology.

    Files in this Data Supplement:

    • Abstract in Arabic - PDF
  • Korean Translation

    Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
    © 2014 American Academy of Neurology.

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    • Korean Translation - PDF

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  • Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
  • EDITORIAL EXPRESSION OF CONCERN: Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
  • Herpes zoster as a risk factor for stroke and TIAA retrospective cohort study in the UK

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