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February 25, 2014; 82 (8) Special Article

Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation

Report of the Guideline Development Subcommittee of the American Academy of Neurology

Antonio Culebras, Steven R. Messé, Seemant Chaturvedi, Carlos S. Kase, Gary Gronseth
First published February 24, 2014, DOI: https://doi.org/10.1212/WNL.0000000000000145
Antonio Culebras
From the Department of Neurology (A.C.), SUNY Upstate Medical University, Syracuse, NY; the Department of Stroke and Neurocritical Care (S.R.M.), Hospital of the University of Pennsylvania and the Pennsylvania Hospital, Philadelphia; the Stroke Program (S.C.), Wayne State University School of Medicine, Detroit, MI; the Department of Neurology (C.S.K.), Boston University School of Medicine and Boston Medical Center, Boston, MA; and the Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City, KS.
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Steven R. Messé
From the Department of Neurology (A.C.), SUNY Upstate Medical University, Syracuse, NY; the Department of Stroke and Neurocritical Care (S.R.M.), Hospital of the University of Pennsylvania and the Pennsylvania Hospital, Philadelphia; the Stroke Program (S.C.), Wayne State University School of Medicine, Detroit, MI; the Department of Neurology (C.S.K.), Boston University School of Medicine and Boston Medical Center, Boston, MA; and the Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City, KS.
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Seemant Chaturvedi
From the Department of Neurology (A.C.), SUNY Upstate Medical University, Syracuse, NY; the Department of Stroke and Neurocritical Care (S.R.M.), Hospital of the University of Pennsylvania and the Pennsylvania Hospital, Philadelphia; the Stroke Program (S.C.), Wayne State University School of Medicine, Detroit, MI; the Department of Neurology (C.S.K.), Boston University School of Medicine and Boston Medical Center, Boston, MA; and the Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City, KS.
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Carlos S. Kase
From the Department of Neurology (A.C.), SUNY Upstate Medical University, Syracuse, NY; the Department of Stroke and Neurocritical Care (S.R.M.), Hospital of the University of Pennsylvania and the Pennsylvania Hospital, Philadelphia; the Stroke Program (S.C.), Wayne State University School of Medicine, Detroit, MI; the Department of Neurology (C.S.K.), Boston University School of Medicine and Boston Medical Center, Boston, MA; and the Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City, KS.
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Gary Gronseth
From the Department of Neurology (A.C.), SUNY Upstate Medical University, Syracuse, NY; the Department of Stroke and Neurocritical Care (S.R.M.), Hospital of the University of Pennsylvania and the Pennsylvania Hospital, Philadelphia; the Stroke Program (S.C.), Wayne State University School of Medicine, Detroit, MI; the Department of Neurology (C.S.K.), Boston University School of Medicine and Boston Medical Center, Boston, MA; and the Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City, KS.
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Full PDF
Citation
Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation
Report of the Guideline Development Subcommittee of the American Academy of Neurology
Antonio Culebras, Steven R. Messé, Seemant Chaturvedi, Carlos S. Kase, Gary Gronseth
Neurology Feb 2014, 82 (8) 716-724; DOI: 10.1212/WNL.0000000000000145

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This article has a correction. Please see:

  • Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation: Report of the Guideline Development Subcommittee of the American Academy of Neurology - April 22, 2014
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    Figure 1 Proportion of patients with ischemic stroke identified with nonvalvular atrial fibrillation, by study

    Studies sorted by monitoring duration. CI = confidence interval; ELR = event loop recorder; HM = Holter monitoring; inptTele = continuous inpatient telemetry; MCOT = mobile cardiac outpatient telemetry; phoneEKG = outpatient transtelephonic EKG monitoring; sEKG = serial EKG; sELR = serial event loop recordings.

  • Figure 2
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    Figure 2 Relative risk reductions of various outcomes in patients with nonvalvular atrial fibrillation receiving various antithrombotic regimens as compared with warfarin or its derivatives

    Acenocoum = acenocoumarol; ASA = acetylsalicylic acid; CI = confidence interval.

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    Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
    © 2014 American Academy of Neurology.

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      Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
      © 2014 American Academy of Neurology.

      Files in this Data Supplement:

      • Korean Translation - PDF

    Disputes & Debates: Rapid online correspondence

    • Author response to correspondence from Dr. Lopez Valle
      • Gary Gronseth, Professor and Vice-Chairman, University of Kansas Medical Centerguidelines@aan.com
      Submitted November 03, 2016
    • Reply to Perez-Gomez et al.
      • Antonio Culebras, Neurologist, SUNY Upstate Medical Universityguidelines@aan.com
      • Antonio Culebras, Syracuse, NY
      Submitted April 02, 2014
    • Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation: Report of the Guideline Development Subcommittee of the American Academy of Neurology
      • Francisco Perez-Gomez, Chief Section of Cardiology, Hospital Clinico San Carlosfpgomez@salud.madrid.org
      • x
      Submitted April 01, 2014
    • Author Response to Hart, Eikelboom NCP Guideline Commentary
      • Antonio Culebras, Neurologist, SUNY Upstate Medical Universityguidelines@aan.com
      • Antonio Culebras, Syracuse, NY; Steven R. Messe, Philadelphia, PA
      Submitted March 24, 2014
    • Regarding a p-value
      • Raul G. Lopez Valle, Staff Physician, Affinity Medical Associatesmemovallemd@yahoo.com
      Submitted March 24, 2014
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