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September 02, 2014; 83 (10) Article

Timing and number of minor infections as risk factors for childhood arterial ischemic stroke

Nancy K. Hills, Stephen Sidney, Heather J. Fullerton
First published August 20, 2014, DOI: https://doi.org/10.1212/WNL.0000000000000752
Nancy K. Hills
From the Departments of Neurology (N.K.H., H.J.F.), Epidemiology and Biostatistics (N.K.H.), and Pediatrics (H.J.F.), University of California, San Francisco; and the Division of Research (S.S.), Kaiser Permanente Northern California, Oakland.
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Stephen Sidney
From the Departments of Neurology (N.K.H., H.J.F.), Epidemiology and Biostatistics (N.K.H.), and Pediatrics (H.J.F.), University of California, San Francisco; and the Division of Research (S.S.), Kaiser Permanente Northern California, Oakland.
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Heather J. Fullerton
From the Departments of Neurology (N.K.H., H.J.F.), Epidemiology and Biostatistics (N.K.H.), and Pediatrics (H.J.F.), University of California, San Francisco; and the Division of Research (S.S.), Kaiser Permanente Northern California, Oakland.
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Citation
Timing and number of minor infections as risk factors for childhood arterial ischemic stroke
Nancy K. Hills, Stephen Sidney, Heather J. Fullerton
Neurology Sep 2014, 83 (10) 890-897; DOI: 10.1212/WNL.0000000000000752

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Article Information

vol. 83 no. 10 890-897
DOI: 
https://doi.org/10.1212/WNL.0000000000000752
PubMed: 
25142897

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received January 9, 2014
  • Accepted in final form May 14, 2014
  • First Published August 20, 2014.

Article Versions

  • Previous version (August 20, 2014 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2014 American Academy of Neurology

Author Disclosures

    1. Nancy K. Hills, PhD,
    2. Stephen Sidney, MD, MPH and
    3. Heather J. Fullerton, MD, MAS
  1. Nancy K. Hills, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Thrasher Research Foundation RAS-A116619 2/1/11-1/31/13 (no-cost extension until 1/31/14) Stimulants and Childhood Stroke (StaCS) This is a case-control study nested within the cohort of the 2.5 million children enrolled in KPMCP from 1993-2007 with the goal of determining whether ADHD medications increase the risk of childhood arterial ischemic stroke.Role: PI

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Stephen Sidney, MD, MPH and
  4. Scientific Advisory Boards:
    1. All Non-Profit Entities: 1.External Scientific Advisory Cmtee for MESA Air Study 2.National Forum for Heart Disease and Stroke Prevention 3.GRADE DSM 4.NHLBI CVD Surveillance Workgroup

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. All Non-Profit Entries: 1.External Scientific Advisory Cmtee for MESA Air Study 2.National Forum for Heart Disease and Stroke Prevention 3.FDA Guest Speaker Review Committee Dec 2011 4.GRADE DSMB 5.NHLBI CVD Surveillance Workgroup

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. The Permanente Medical Group

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Funded as principal investigator on NHLBI Contract N01 HC-48050 12/30/83-6/30/18; Funded as principal investigator on NINDS U54NS081760 10/1/12-9/30/17; Funded as co-investigator on NINDS U54NS081760 10/1/12-9/30/17; Funded as co-investigator on NIDDK/ GHRI R01DK092317 10/1/12-9/30/16; Funded as co-investigator on AHA/UCSF 12 EIA 9130050 A119064 1/1/12-12/31/14

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Heather J. Fullerton, MD, MAS
  6. Scientific Advisory Boards:
    1. I serve on a DSMB for the NIH for clinical trials related to sickle cell disease and stroke.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. R01 NS062820HJ (PI) NIH/NINDS Vascular Effects of Infection in Pediatric Stroke (VIPS) 08/05/2009 - 07/31/2014; R01 NS062820-02S1(PI) NIH/NINDS Global Health Supplement to VIPS 08/01/2010 - 07/31/2011; K02 NS053883(PI) NIH/NINDS Independent Scientist Award The Role of Infection in Childhood Stroke 06/01/2006 - 08/31/2011 R01 HL096789-01RJ (Co-investigator) NIH/HSOD Prevention of Stroke after STOP (POST-STOP) 07/01/2009 - 06/30/2014

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. American Heart Association Established Investigator Award

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Departments of Neurology (N.K.H., H.J.F.), Epidemiology and Biostatistics (N.K.H.), and Pediatrics (H.J.F.), University of California, San Francisco; and the Division of Research (S.S.), Kaiser Permanente Northern California, Oakland.
  1. Correspondence to Dr. Fullerton: FullertonH{at}neuropeds.ucsf.edu
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