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September 16, 2014; 83 (12) Article

Course of psychiatric symptoms and global cognition in early Parkinson disease

Patricia de la Riva, Kara Smith, Sharon X. Xie, Daniel Weintraub
First published August 15, 2014, DOI: https://doi.org/10.1212/WNL.0000000000000801
Patricia de la Riva
From the Department of Neurology (P.d.l.R.), University Hospital Donostia, San Sebastián, Spain; Department of Biostatistics and Epidemiology (S.X.X.) and Departments of Neurology and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania (K.S.), Philadelphia; and Department of Veterans Affairs (D.W.), Philadelphia VA Medical Center.
MD
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Kara Smith
From the Department of Neurology (P.d.l.R.), University Hospital Donostia, San Sebastián, Spain; Department of Biostatistics and Epidemiology (S.X.X.) and Departments of Neurology and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania (K.S.), Philadelphia; and Department of Veterans Affairs (D.W.), Philadelphia VA Medical Center.
MD
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Sharon X. Xie
From the Department of Neurology (P.d.l.R.), University Hospital Donostia, San Sebastián, Spain; Department of Biostatistics and Epidemiology (S.X.X.) and Departments of Neurology and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania (K.S.), Philadelphia; and Department of Veterans Affairs (D.W.), Philadelphia VA Medical Center.
PhD
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Daniel Weintraub
From the Department of Neurology (P.d.l.R.), University Hospital Donostia, San Sebastián, Spain; Department of Biostatistics and Epidemiology (S.X.X.) and Departments of Neurology and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania (K.S.), Philadelphia; and Department of Veterans Affairs (D.W.), Philadelphia VA Medical Center.
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Full PDF
Citation
Course of psychiatric symptoms and global cognition in early Parkinson disease
Patricia de la Riva, Kara Smith, Sharon X. Xie, Daniel Weintraub
Neurology Sep 2014, 83 (12) 1096-1103; DOI: 10.1212/WNL.0000000000000801

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Article Information

vol. 83 no. 12 1096-1103
DOI: 
https://doi.org/10.1212/WNL.0000000000000801
PubMed: 
25128183

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received March 23, 2014
  • Accepted in final form June 23, 2014
  • First Published August 15, 2014.

Article Versions

  • Previous version (August 15, 2014 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2014 American Academy of Neurology

Author Disclosures

    1. Patricia de la Riva, MD,
    2. Kara Smith, MD,
    3. Sharon X. Xie, PhD and
    4. Daniel Weintraub, MD
  1. Patricia de la Riva, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1)Group of Young Neurologists of the Spanish Society of Neurology

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Kara Smith, MD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. I receive an educational grant from Medtronic as a partial source of funding for my fellowship.

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Sharon X. Xie, PhD and
  6. Scientific Advisory Boards:
    1. Dr. Xie served as a consultant to Roche on a clinical trial unrelated to this study.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Alzheimer's & Dementia, Associate Editor, 2013-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Dr. Xie received funding from MJ Fox foundation and NIH grant R21-AT005230. Dr. Xie is currently funded by NIH grants P30-AG010124, P50-NS053488,P01-AG032953, P01-AG017586, R01-AT005074, R01-AG040271, and U01-NS082134.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Daniel Weintraub, MD
  8. Scientific Advisory Boards:
    1. Commercial - Pfizer, Teva Pharmaceuticals, Avanir Pharmaceuticals, Merck & Co., Lundbeck Inc., UCB, Bristol- Myers Squib Company, Novartis, Clintrex, Theravance, Medivation Non-profit - CHDI, ADCS

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Serves on Editorial Board of Movement Disorders Journal and Journal of Parkinson's Disease

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. Licensing fees from the University of Pennsylvania for the QUIP and QUIP-RS

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Novartis Pharmaceuticals, PI, 2011-

    Research Support, Government Entities:
    1. NINDS, P50 NS053488, Investigator, 2007- NINDS, R01NS065087, Investigator, 2009-2012 NIA, RO1AG031348, Investigator, 2008- NIA, U19 AG10483-22, DSMB Chair, 2013-

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Michael J. Fox Foundation for Parkinson's Research, PI, 2009-2011 Michael J. Fox Foundation for Parkinson's Research, PI, 2011- Michael J. Fox Foundation for Parkinson's Research, Investigator, 2011-

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. Licensing fees from the University of Pennsylvania for licensing of Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease.

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. Expert testimony for defense in 2012-2014 in two lawsuits related to impulse control disorders in Parkinson's disease

  1. From the Department of Neurology (P.d.l.R.), University Hospital Donostia, San Sebastián, Spain; Department of Biostatistics and Epidemiology (S.X.X.) and Departments of Neurology and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania (K.S.), Philadelphia; and Department of Veterans Affairs (D.W.), Philadelphia VA Medical Center.
  1. Correspondence to Dr. de la Riva: patricia.delariva{at}gmail.com

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