Skip to main content
Advertisement
  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Specialty Sites
    • COVID-19
    • Practice Current
    • Practice Buzz
    • Without Borders
    • Equity, Diversity and Inclusion
    • Innovations in Care Delivery
  • Collections
    • Topics A-Z
    • Residents & Fellows
    • Infographics
    • Patient Pages
    • Null Hypothesis
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center

Advanced Search

Main menu

  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Specialty Sites
    • COVID-19
    • Practice Current
    • Practice Buzz
    • Without Borders
    • Equity, Diversity and Inclusion
    • Innovations in Care Delivery
  • Collections
    • Topics A-Z
    • Residents & Fellows
    • Infographics
    • Patient Pages
    • Null Hypothesis
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Residents & Fellows

User menu

  • Subscribe
  • My Alerts
  • Log in

Search

  • Advanced search
Neurology
Home
The most widely read and highly cited peer-reviewed neurology journal
  • Subscribe
  • My Alerts
  • Log in
Site Logo
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Residents & Fellows

Share

April 06, 2015; 84 (14 Supplement) April 22, 2015

Validation of strategies to streamline high and low contrast visual acuity testing in ALS subjects (P5.317)

Lindsay Boven, Qin Li Jiang, Heather Moss
First published April 8, 2015,
Lindsay Boven
3University of Illinois Medical College Chicago IL United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Qin Li Jiang
2University of Illinois At Chicago Chicago IL United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Heather Moss
1University of Ilinois At Chicago Chicago IL United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Citation
Validation of strategies to streamline high and low contrast visual acuity testing in ALS subjects (P5.317)
Lindsay Boven, Qin Li Jiang, Heather Moss
Neurology Apr 2015, 84 (14 Supplement) P5.317;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Permissions

Make Comment

See Comments

Downloads
0

Share

  • Article
  • Info & Disclosures
Loading

Abstract

OBJECTIVE/BACKGROUND: Afferent visual system disorders are included in the phenotypic spectrum Amyotrophic Lateral Sclerosis (ALS). High and low contrast visual acuity (HCVA and LCVA) are potential quantitative clinical markers of this dysfunction. Gold standard clinical research protocols for HCVA and LCVA measurements are difficult to implement in a neurology clinic. Pinhole is a possible substitute for refraction, which is time consuming requiring specialized equipment and personnel. Charts presented on tablets are a potential substitute for retro-illuminated charts, which are bulky and less readily available. The purpose of this study is to evaluate the effect of substituting pinhole for refraction and tablet charts for retro-illuminated charts on HCVA and LCVA in ALS patients. DESIGN/METHODS: Monocular HCVA and 2.5[percnt] LCVA were measured at 2m in 8 ALS subjects using two chart conditions (retro-illuminated Sloan charts, Ipad presented charts) and two correction conditions (spherical refraction, pinhole). Number of letters correctly identified were compared between chart conditions and between correction conditions. Differences less than 5 letters (1 line) were considered comparable. RESULTS: HCVA was comparable between correction conditions and between chart conditions for 6/8 (75[percnt]) and 7/8 (88[percnt]) subjects respectively. LCVA was comparable between correction conditions and between chart conditions for 3/8 (38[percnt]) and 6/8 (75[percnt]) respectively. Incomparable values favored pinhole for HCVA and spherical refraction for LCVA. CONCLUSIONS: In this pilot study, we find that HCVA and LCVA tablet presented charts produce comparable measurements to gold standard retroilluminated charts in greater than 75[percnt] of ALS subjects. Pinhole correction is comparable to spherical refraction for measurements of HCVA but not LCVA. HCVA measurements with pinhole and tablet charts are less burdensome for ALS patients and research staff without sacrificing accuracy. Pinhole is not a suitable modification for LCVA measurements. Study Supported by: K23 EY024345, P30 EY01792, unrestricted departmental grant from Research to Prevent Blindness

Disclosure: Dr. Boven has nothing to disclose. Dr. Jiang has nothing to disclose. Dr. Moss has nothing to disclose.

Wednesday, April 22 2015, 2:00 pm-6:30 pm

  • Copyright © 2015 by AAN Enterprises, Inc.

Disputes & Debates: Rapid online correspondence

No comments have been published for this article.
Comment

NOTE: All authors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.

  • Stay timely. Submit only on articles published within 6 months of issue date.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • 200 words maximum.
  • 5 references maximum. Reference 1 must be the article on which you are commenting.
  • 5 authors maximum. Exception: replies can include all original authors of the article.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Disputes & Debates Submission Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top
  • Article
  • Info & Disclosures
Advertisement

Related Articles

  • No related articles found.

Alert Me

  • Alert me when eletters are published
Neurology: 96 (16)

Articles

  • Ahead of Print
  • Current Issue
  • Past Issues
  • Popular Articles
  • Translations

About

  • About the Journals
  • Ethics Policies
  • Editors & Editorial Board
  • Contact Us
  • Advertise

Submit

  • Author Center
  • Submit a Manuscript
  • Information for Reviewers
  • AAN Guidelines
  • Permissions

Subscribers

  • Subscribe
  • Activate a Subscription
  • Sign up for eAlerts
  • RSS Feed
Site Logo
  • Visit neurology Template on Facebook
  • Follow neurology Template on Twitter
  • Visit Neurology on YouTube
  • Neurology
  • Neurology: Clinical Practice
  • Neurology: Genetics
  • Neurology: Neuroimmunology & Neuroinflammation
  • AAN.com
  • AANnews
  • Continuum
  • Brain & Life
  • Neurology Today

Wolters Kluwer Logo

Neurology | Print ISSN:0028-3878
Online ISSN:1526-632X

© 2021 American Academy of Neurology

  • Privacy Policy
  • Feedback
  • Advertise