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April 14, 2015; 84 (15) Article

Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland

James Rooney, Alice Vajda, Mark Heverin, Marwa Elamin, Arlene Crampsie, Russell McLaughlin, Anthony Staines, Orla Hardiman
First published March 13, 2015, DOI: https://doi.org/10.1212/WNL.0000000000001477
James Rooney
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Alice Vajda
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Mark Heverin
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Marwa Elamin
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Arlene Crampsie
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Russell McLaughlin
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Anthony Staines
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Orla Hardiman
From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
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Full PDF
Citation
Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland
James Rooney, Alice Vajda, Mark Heverin, Marwa Elamin, Arlene Crampsie, Russell McLaughlin, Anthony Staines, Orla Hardiman
Neurology Apr 2015, 84 (15) 1537-1544; DOI: 10.1212/WNL.0000000000001477

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Article Information

vol. 84 no. 15 1537-1544
DOI: 
https://doi.org/10.1212/WNL.0000000000001477
PubMed: 
25770197

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received September 30, 2014
  • Accepted in final form November 24, 2014
  • First Published March 13, 2015.

Article Versions

  • Previous version (March 13, 2015 - 13:01).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2015 American Academy of Neurology

Author Disclosures

    1. James Rooney, MSc,
    2. Alice Vajda, PhD,
    3. Mark Heverin, MSc,
    4. Marwa Elamin, PhD,
    5. Arlene Crampsie, PhD,
    6. Russell McLaughlin, PhD,
    7. Anthony Staines, PhD and
    8. Orla Hardiman, MD
  1. James Rooney, MSc,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Alice Vajda, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Mark Heverin, MSc,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Marwa Elamin, PhD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Arlene Crampsie, PhD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Russell McLaughlin, PhD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Anthony Staines, PhD and
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Orla Hardiman, MD
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Academic Unit of Neurology (J.R., A.V., M.H., M.E., R.M., O.H.), Trinity Biomedical Sciences Institute, Trinity College, Dublin; School of Geography, Planning & Environmental Policy (A.C.), University College Dublin Belfield, Dublin; School of Nursing and Human Sciences (A.S.), Dublin City University; and Department of Neurology (O.H.), Beaumont Hospital, Ireland.
  1. Correspondence to James Rooney: jrooney{at}rcsi.ie
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Cited By...

  • 19 Citations
  • Google Scholar

Letters: Rapid online correspondence

  • Spatial Clustering of ALS in Ireland: Response to Bradley et al.
    • James P. Rooney, PhD Student, Trinity College Dublinjrooney@rcsi.ie
    • Anthony Staines, Dublin, Ireland; Orla Hardiman, Dublin, Ireland
    Submitted May 29, 2015
  • Re: Rooney et al. Spatial cluster analysis of population ALS risk in Ireland. Neurology 2015;84:1537-1544.
    • Walter G Bradley, Professor of Neurology, University of Miami School of Medicinew.bradley@miami.edu
    • Elijah W. Stommel , Hanover, NH; Xun Shi, Hanover, NH; Nathan M Torbick, Newmarket, NH; Tracie A Caller, Hanover, NH; Clive E Sabel, Bristol, UK
    Submitted May 19, 2015
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