Sleep-disordered breathing advances cognitive decline in the elderly
Citation Manager Formats
Make Comment
See Comments

Article Information
- Received October 16, 2014
- Accepted in final form January 28, 2015
- First Published April 15, 2015.
Article Versions
- Previous version (April 15, 2015 - 13:00).
- You are viewing the most recent version of this article.
Author Disclosures
- Ricardo S. Osorio, MD,
- Tyler Gumb, BA,
- Elizabeth Pirraglia, MA,
- Andrew W. Varga, PhD, MD,
- Shou-en Lu, PhD,
- Jason Lim, BA,
- Margaret E. Wohlleber, BA,
- Emma L. Ducca, BA,
- Viachaslau Koushyk, MD,
- Lidia Glodzik, MD,
- Lisa Mosconi, PhD,
- Indu Ayappa, PhD,
- David M. Rapoport, MD,
- Mony J. de Leon, EdD;
- For the Alzheimer's Disease Neuroimaging Initiative
- Ricardo S. Osorio, MD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
(1) NIH/NIA AG035137, Research Scientist 2010-2015 (2) NIH/NIA AG13616, Research Scientist 2010-2015 (3) NIH/NIA AG032554, Research Scientist 2010-2015 (4) NIH/NIA AG022374, Research Scientist 2008-2012
NONE
Alzheimer?s Association IIRG-09-132030 Research Scientist 2009-2013
NONE
NONE
NONE
NONE
NONE
NONE
- Tyler Gumb, BA,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Elizabeth Pirraglia, MA,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Andrew W. Varga, PhD, MD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
(1) NYU Physician Scientist Training Program
(1) American Sleep Medicine Foundation
NONE
NONE
NONE
NONE
NONE
NONE
- Shou-en Lu, PhD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Jason Lim, BA,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Margaret E. Wohlleber, BA,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Emma L. Ducca, BA,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Viachaslau Koushyk, MD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Lidia Glodzik, MD,
a member of a review panel for Agence Nationale de la Recherche
NONE
received an honorarium from Roche Pharma
Aassociate Editor of Journal of Alzheimer's Disease
NONE
NONE
NONE
NONE
NONE
NONE
NONE
Forest Laboratories NAM-MD-68
2 R01AG013616 study neurologist 2 R01 AG022374 study neurologist 2 P30AG008051 study neurologist 2 R01 AG012101 study neurologist 1 R01 HL111724 PI 1 RC2AG036502 study neurologist 1 R01HL118624 study neurologist
NONE
Alzheimer?s Association NIRG-09-132490 Alzheimer?s Association, IIRG 91038
NONE
NONE
NONE
NONE
NONE
NONE
- Lisa Mosconi, PhD,
NONE
NONE
1. Travel honoraria from the MIT Media Lab 2. Travel honoraria from the Culinary Institute of America 1. Speaking honoraria from the MIT Media Lab
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Indu Ayappa, PhD,
NONE
NONE
NONE
NONE
Dr Ayappa holds multiple US and foreign patents covering techniques and analysis algorithms for the diagnosis of sleep apnea and techniques for administering CPAP.
NONE
NONE
(i) Fisher and Paykel Healthcare Ltd
NONE
NONE
NONE
Dr Ayappa has received support for research from the industry in the past 24 months: research grants from Fisher & Paykel Healthcare
(i) NIOSH/CDC, 1U01OH010415-01 co-PI, from 2012- (ii) NIH,1K24HL109156-01A1 PI, 2013- (iii) NIH, 1R01HL118624- 01 , investigator, 2014 (iv)NIH,1R25 HL105444, investigator, 2010
(i) NYU School of Medicine
NONE
NONE
NONE
Dr Ayappa holds multiple US and foreign patents covering techniques and analysis algorithms for the diagnosis of OSAHS and techniques for administering CPAP. Several of these have been licensed to Fisher & Paykel Healthcare and Advanced Brain Monitoring.
NONE
NONE
NONE
- David M. Rapoport, MD,
Dr Rapoport serves on scientific advisory boards for: Fisher & Paykel Healthcare and Luna Medical.
NONE
NONE
NONE
Dr. Rapoport holds multiple US and foreign patents covering techniques and analysis algorithms for the diagnosis of OSAHS and techniques for administering CPAP. Several of these have been licensed to Biologics, Fisher & Paykel Healthcare, Advanced Brain Monitoring, and Tyco (Sefam).
NONE
NONE
Fisher and Paykel Healthcare
NONE
NONE
NONE
Fisher and Paykel Healthcare - research grant awarded to NYU
NIH NHLBI - multiple R01/R21/K24
New York University Medical Center grant
Foundation for Research in Sleep Disorders
NONE
Fisher and Paykel Healthcare - CPAP technologies - assigned to NYU
Fisher and Paykel Healthcare - CPAP technologies - assigned to NYU
NONE
NONE
NONE
- Mony J. de Leon, EdD;
Non-profit French Alzheimer Foundation DZNE German Alzheimer Inititive
NONE
Travel funding non profit French Alzheimer Foundation DZNE German Alzheimer Inititive NIH external advisory meetings
Dementia present JAD present
Image analysis patents managed by NYU and licensed to Abient
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NIH RO1 and PO3 grant support
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- For the Alzheimer's Disease Neuroimaging Initiative
- From the Center for Brain Health (R.S.O., T.G., E.P., M.E.W., L.G., L.M., M.J.d.L.) and Division of Pulmonary, Critical Care, and Sleep Medicine (A.W.V., J.L., E.L.D., V.K., I.A., D.M.R.), NYU School of Medicine, New York, NY; and Department of Biostatistics (S.-e.L.), Rutgers School of Public Health, Piscataway, NJ.
- Correspondence to Dr. Osorio: ricardo.osorio{at}nyumc.org
Article usage
Cited By...
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Dr. Nicole Sur and Dr. Mausaminben Hathidara
► Watch
Topics Discussed
Alert Me
Recommended articles
-
Five New Things
Management of sleep apnea in the neurology patientFive new thingsRachel E. Salas, Rohini Chakravarthy, Alex Sher et al.Neurology: Clinical Practice, February 17, 2014 -
Article
Prevalence and correlates of periodic limb movements in OSA and the effect of CPAP therapyRohit Budhiraja, Sogol Javaheri, Milena K. Pavlova et al.Neurology, December 27, 2019 -
Review
Treatment options for obstructive sleep apneaPatrick Pavwoski, Anita Valanju Shelgikar et al.Neurology: Clinical Practice, November 10, 2016 -
Article
Witnessed apneas are associated with elevated tau-PET levels in cognitively unimpaired elderlyDiego Z. Carvalho, Erik K. St. Louis, Christopher G. Schwarz et al.Neurology, March 26, 2020