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January 20, 2015; 84 (3) Article

Absence of neurocognitive effect of hepatitis C infection in HIV-coinfected people

David B. Clifford, Florin Vaida, Yu-Ting Kao, Donald R. Franklin, Scott L. Letendre, Ann C. Collier, Christina M. Marra, Benjamin B. Gelman, Justin C. McArthur, Susan Morgello, David M. Simpson, Igor Grant, Robert K. Heaton, For the CHARTER Group
First published December 10, 2014, DOI: https://doi.org/10.1212/WNL.0000000000001156
David B. Clifford
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Florin Vaida
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Yu-Ting Kao
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Donald R. Franklin
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Scott L. Letendre
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Ann C. Collier
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Christina M. Marra
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Benjamin B. Gelman
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Justin C. McArthur
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Susan Morgello
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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David M. Simpson
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Igor Grant
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Robert K. Heaton
From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
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Citation
Absence of neurocognitive effect of hepatitis C infection in HIV-coinfected people
David B. Clifford, Florin Vaida, Yu-Ting Kao, Donald R. Franklin, Scott L. Letendre, Ann C. Collier, Christina M. Marra, Benjamin B. Gelman, Justin C. McArthur, Susan Morgello, David M. Simpson, Igor Grant, Robert K. Heaton, For the CHARTER Group
Neurology Jan 2015, 84 (3) 241-250; DOI: 10.1212/WNL.0000000000001156

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Article Information

vol. 84 no. 3 241-250
DOI: 
https://doi.org/10.1212/WNL.0000000000001156
PubMed: 
25503616

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received April 7, 2014
  • Accepted in final form August 18, 2014
  • First Published December 10, 2014.

Article Versions

  • Previous version (December 10, 2014 - 13:01).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2014 American Academy of Neurology

Author Disclosures

    1. David B. Clifford, MD,
    2. Florin Vaida, PhD,
    3. Yu-Ting Kao, MS,
    4. Donald R. Franklin, BS,
    5. Scott L. Letendre, MD,
    6. Ann C. Collier, MD,
    7. Christina M. Marra, MD,
    8. Benjamin B. Gelman, MD, PhD,
    9. Justin C. McArthur, MBBS,
    10. Susan Morgello, MD,
    11. David M. Simpson, MD,
    12. Igor Grant, MD,
    13. Robert K. Heaton, PhD;
    14. For the CHARTER Group
  1. David B. Clifford, MD,
  2. Scientific Advisory Boards:
    1. Amgen - PML Adjudication Board 2012 - Biogen Idec/Quintiles - DSMB for progressive MS trial 2011 - BMS - PML Adjudication Committee 2012 - Genentech PML Advisory Board regarding PML 2007 - 2014 Genzyme DSMB for CARE MS Study 2008-2011 Pfizer DMC for MAdCAM study 2011 - Millennium - Chair PML IAC for clinical trials 2009 - 2014 Millennium - ADCETRIS trial adjudication committee member 2012 - Genentech - PML Adjudication Committee (Chair) Etrolizumab trials 2014 - Sanofi - DMSB for MS trial 2014 -

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Sun Pharmaceuticals - Speaker Honorarium - Symposium in Pune India (2013) Emory University - Speaker Honorarium for grand rounds University of Kansas - Speaker Honorarium for grand rounds

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Millennium Consulting regarding PML 2007-2014 Genzyme consultant 2009-2013 Biogen Idec scientific advisor regarding PML 2005-2014 IAS-USA speaker honorarium 2012 CMSC/ACTRIMS speaker honorarium 2012 ECTRIMS spearker honorarium 2012 Drinker, Biddle, Reath - Chair Scientific Advisory Committee of PML Consortium 2010 - Cytheris - PML trial design, FDA 2012 - 2013 Novartis - Case review consult for PML diagnosis - 2014

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Lilly (DIAN - TU) 2013 - Roche (DIAN - TU) 2013 -

    Research Support, Government Entities:
    1. NIH UO1 A169495 AIDS Clinical Trials Unit 2013-2020 NIH U10 NS077384 NeuroNEXT Trials Unit 2011- 2018 NIMH 22005 CHARTER Project (Washington U Site PI) 2007 - 2015 NIH R01 NR012907 (NINR,Ances - PI), Co-investigator, 2010- 2015 NIH R01 NR012907 (NINR, Ances - PI), Co-investigator, 2011-2016 DIAN TTU 12-243040 (Alzheimer Association, Bateman PI), Co-investigator, 2012-2016.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. Arnold Todoro & Welch (legal consultation)2012 - Rainey, Kizer, Reviere, Bell (case review 2013 Silver and Deboskey PC (legal case review) 2013 Drinker Biddle and Reath LLC (PML Consortium Scientific Advisory Board) 2012 -

  3. Florin Vaida, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Research Methodology Section Editor for the Californian Journal of Health Promotion Editor, ISRN-AIDS Frontiers in Genetics, Research Editor

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Statistical Consultant for Washington University in St Louis.

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NIH MH22005HIV, Investigator, 2006-2011 NIH MH083552, Investigator, 2008-2013 NIH MH62512, Investigator, 2007-2011 NIH AI074521, Investigator, 2007-2012 NIH MH085608, Investigator, 2009-2013 NIH MH58076, Investigator, 2008-2011

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Yu-Ting Kao, MS,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. (1) Eli Lilly and company, Sr. Statistician-computation, since 8/4/2014

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Donald R. Franklin, BS,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NIMH N01 MH22005; HHSN271201000036C; HHSN271201000030C, Center Manager 2006-present

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Scott L. Letendre, MD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. (1) ViiV Healthcare, 2013 (2) Abbvie, 2013

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Merck & Co., Inc., 2012

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1) GlaxoSmithKline, Paid to the University of California (2) Merck & Co., Inc., Paid to the University of California (3) Abbvie, Paid to the University of California

    Research Support, Government Entities:
    1. (1) NIH, U01 MH083506, consultant, 2012 (2) NIH, R01 MH58076, co-investigator, 2012 (3) NIH, P50 DA26306, co-investigator, 2012, 2013 (4) NIH, R01 MH73433, co-investigator, 2012 (5) NIH, N01 MH22005, co-investigator, 2012, 2013 (6) NIH, P30 MH62512, co-investigator, 2012, 2013 (7) NIH, R01 MH78748, co-investigator, 2012 (8) NIH, R21 MH85610, principal investigator, 2012 (9) NIH, R01, MH92225, principal investigator, 2012, 2013 (10) NIH, K24, MH097673, principal investigator, 2013

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Ann C. Collier, MD,
  12. Scientific Advisory Boards:
    1. (1) Data and Safety Monitoring Board for Merck & Co.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1) Schering-Plough - past research contract (2) Merck & Co.- past research contract (3) Roche Molecular Systems - past research contract

    Research Support, Government Entities:
    1. (1) NIH/NIMH, N01 MH22005, Collier Co-PI on Subcontract, 3/12/03-8/31/15 (2) NIH/NIAID, UM1 AI 069481, Collier PI on Subcontract, 12/10/13 ? 11/30/2020 (3) NIH/NIAID, UM1 AI 069434, Collier, PI, 1/1/07-5/30/14 (4) NIH/NIAID, P01 AI 057005, Collier, Core PI, 10/01/03- 6/30/15 (5)NIH/NIMH, R01 NS082120, Collier Co-Investigator, 7/1/13-3/31/18 (6)NIH/NIAID, R01 AI090783, Collier, Co-Investigator, 6/1/10-5/31/14 (7)NIH/NIAID, UM1 AI068636, Co-Investigator, 6/1/13- 1/31/14 (8)NIH/NINDS, RC1NS068904, Collier, Co-Investigator, 9/22/09-8/31/12 (9)NIH/NIAID, AI069918, Co-Investigator of Subcontract, 4/1/06-6/30/16 (10)Social and Scientific Systems (pass through funds from NIH), CRB-SSS-5-11-000930/CRB-DCR01-5-09-00291, Collier, PI on contract, 2/2/11-3/31/13 (11)Social and Scientific Systems, pass through funds from NIH, BRS-ACURE-S-11-00046-001329, Collier, PI of contract, 6/1/10-5/31/12 Stock/Stock Options, Medical Equipment & Materials: (1) Abbott Laboratories, former stock owner, sold stock 8/23/12 (2) Bristol-Myers-Squibb, former stock owner, sold stock 8/23/12 (3) Johnson and Johnson, former stock owner, sold stock 8/23/12 (4) Pfizer, former stock owner, sold stock 8/23/12

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Christina M. Marra, MD,
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. I receive royalties from UpToDate for an article that I wrote on neurosyphilis. I receive royalties for a text entitled Infections of the Central Nervous System 4d ed, published by LWW in 2014.

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. 1) NIH, NS34235, PI, 1996-2014; NIH, NS082120, PI, 2013-14; NIH, MH22005, Co-investigator, 2003-2014; NIH, AI094126, Co-investigator, 2012-2014; NIH, AI069434, Site Neurologist, 2007-2013; NIH, AI094122, Co-investigator, 2011-2013; NIH, NS32228, Co-investigator, 1997-2011; NIH, AI068636, PI on subcontract, 2011-2014

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Benjamin B. Gelman, MD, PhD,
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. 1) National Institute of Mental Health, U01MH083507, 2008- 2010. 2) National Institute of Mental Health, R01MH079886, 2006- 2010. 3) National Institute of Mental Health, N01MH022005, 2003- 2010.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  17. Justin C. McArthur, MBBS,
  18. Scientific Advisory Boards:
    1. Relevare, scientific advisory board. 2006 - present. Stock options

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. Murphy JC, Szczepanowski RP, Schneider W, Meyer RA, McArthur JC, Polydefkis M. Device for thermal stimulation of small neural fibers. World Intellectual Property Organization,International Publication Number WO 03/040672 A2, 15 May 2003. Murinson BB, McArthur JC. Medical Device for Treatment of Ulnar Neuropathy. UlnarGuard ? (JHU Ref: 4545) Nath A, Hoke A, McArthurJC. Immunophilin ligand treatment of antiretroviral toxic neuropathy (Provisional application number 60/466,650)

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Biogen Idec 2009- (PI on clinical trial) Pfizer 2010 (PI on clinical trial)

    Research Support, Government Entities:
    1. NIH research funding 1986 - present

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Foundation for Peripheral Neuropathy research grant 2008- present

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  19. Susan Morgello, MD,
  20. Scientific Advisory Boards:
    1. Not-for-profit; Advisory Board member, Temple University Comprehensive NeuroAIDS Center (CNAC)

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Journal of Neurovirology, editorial board, 2001 to present, no compensation received

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NIH: R24MH59724, U01MH083501, U24MH100931, PI, 1998-present R25MH080663, PI, 2007-present N01MH22005, Subsite PI, 2001-present R01DA037611, Subsite PI, 2014

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  21. David M. Simpson, MD,
  22. Scientific Advisory Boards:
    1. Scientific advisory board: Allergan,Merz, Astellas, Acorda

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Speaker honoraria: Allergan

    Editorial Boards:
    1. AIDS Patient Care (2008-current)

    Patents:
    1. NONE

    Publishing Royalties:
    1. Neuropathic Pain: Mechanisms, Diagonosis and Management; Oxford; 2012

    Employment, Commercial Entity:
    1. Icahn School of Medicine at Mount Sinai

    Consultancies:
    1. Allergan, Acorda, Astellas

    Speakers' Bureaus:
    1. Allergan

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Allergan, Merz, Ipsen, US Worldmeds, Astellas, Viromed, CSL Behring

    Research Support, Government Entities:
    1. NINDS: R01-NS328-05-co-inv; R24 MH59724-co-inv;R01-NS- 41198-co-inv; NIMH-00-AI-0005-co-PI

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Peripheral Neuropathy Foundation

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. Proctor and Gamble: 2012-2014

  23. Igor Grant, MD,
  24. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Abbott Pharmaceuticals speaker fee AbbVie speaker fee

    Editorial Boards:
    1. (1)Journal of the International Neuropsychological Society, Associate Editor, 2002-2004, (2) Journal of Neurovirology, Associate Editor, 2002-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. Abbott Pharmaceuticals

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) NIDA, DA26306, PI, 2009-present, (2) NIMH, MH83506, PI, 2002-present, (3) NIMH, HHSN271201000036C, PI, 2010-present, (4) NIMH, HHSN271201000030C, PI, 2010-present, (5) NIMH, MH094159, Co-I, 2011-present (6) NIMH, MH62512, Co-I, 2011-present, (7) NIMH, MH78748, Co-I, 2007-2013, (8) NIMH, MH83552, Co-I, 2008-2013, (9) NIA, AG15301, PI, 2002-2012

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  25. Robert K. Heaton, PhD;
  26. Scientific Advisory Boards:
    1. (1) NINCDS, advisor, 2007-2010

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. (1) Journal of the International Neuropsychological Society, editorial board, 2000-present, (2) Journal of Clinical and Experimental Neuropsychology, editorial board, 2000-present, (3) The Clinical Neuropsychologist, editorial board, 2000-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. (1) Revised Comprehensive Norms for and Expanded Halstead-Reitan Battery: Demographically Adjusted Neuropsychological Norms for African American and Caucasian Adults, Psychological Assessment Resources, Inc., 1991-present (2) Revised Comprehensive Norms for and Expanded Halstead-Reitan Battery: Demographically Adjusted Neuropsychological Norms for African American and Caucasian Adults Scoring Program, Psychological Assessment Resources, Inc., 1994-present (3) Wisconsin Card Sorting Test Manual-Revised and Expanded, Psychological Assessment Resources, Inc., 1991-present

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1)NIH P30 MH62512, Co-Investigator, 2006-2010, (2)NIH P50 DA26306, Co-Investigator, 2009-2010, (3) NIH P01 DA12065, Co-Investigator, 2005-2010, (4) NIH R01 MH60720, Co-Investigator, 2006-2010, (5) NIH R01 MH73433, Principal Investigator, 2005-2010, (6) NIH N01 MH22005, Co-Investigator, 2002-2010, (7) NIH R01 MH58076, Co-Investigator, 2006-2010, (8) NIH R01 MH78748,Co-Investigator, 2007-2010, (9) NIH R01 MH78737, Co-Investigator, 2007-2010, (10) NIH U01 MH83506, Co-Investigator, 2008-2010, (11) NIH R01 MH83552,Co-Investigator, 2008-2010, (12) NIH R01 MH81861, Co-Investigator, 2008-2010, (13) NIH P30MH062512-11, Principal Investigator, 2011-2016.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  27. For the CHARTER Group
  1. From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.
  1. Correspondence to Dr. Clifford: cliffordd{at}wustl.edu
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