Congenital mirror movements (CMM) disorder is characterized by involuntary movements of one side of the body that accompany and mirror intentional movements on the opposite side (OMIM #157600).1 CMM mostly involve the hands, and affected subjects are unable to perform pure unimanual movements or skilled dissociated movements of the 2 hands. We show a 33-year-old patient with CMM with no abnormality in DCC or RAD51, the known culprit genes (video on the Neurology® Web site at Neurology.org).2 He had always dreamed of becoming a piano player but was unable to play properly with both hands despite intensive training. He became an opera singer instead.
Footnotes
Supplemental data at Neurology.org
Author contributions: Aurélie Méneret: drafting/revising the manuscript, analysis or interpretation of data, accepts responsibility for conduct of research and final approval. Quentin Welniarz: analysis or interpretation of data, accepts responsibility for conduct of research and final approval, acquisition of data. Oriane Trouillard: analysis or interpretation of data, accepts responsibility for conduct of research and final approval. Emmanuel Roze: drafting/revising the manuscript, study concept or design, analysis or interpretation of data, accepts responsibility for conduct of research and final approval, study supervision.
Study funding: No targeted funding reported.
Disclosure: A. Méneret received a research grant from AP-HP and received travel funding from ANAINF, JNLF, and the European Federation of the Neurological Societies. Q. Welniarz and O. Trouillard report no disclosures relevant to the manuscript. E. Roze is the recipient of a grant “poste d'accueil” AP-HP/CNRS. He received research support from INSERM (COSSEC), AP-HP (DRC-PHRC), Fondation pour la Recherche sur le Cerveau (FRC), the Dystonia Coalition (Pilot project), Ipsen, Merz-Pharma, Novartis, Teva, Lundbeck, and Orkyn; served on scientific advisory boards for Orkyn, Ipsen, and Merz-Pharma; received speech honorarium from Novartis, Teva, and Orkyn; and received travel funding from Teva, Novartis, the Dystonia Coalition, the Movement Disorders Society, the World Federation of Neurology Association of Parkinsonism and Related Disorders, and International Federation of Clinical Neurophysiology. Go to Neurology.org for full disclosures.
- © 2015 American Academy of Neurology
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