Share

November 24, 2015; 85 (21) Article

Stroke risk stratification in acute dizziness presentations

A prospective imaging-based study

Kevin A. Kerber, William J. Meurer, Devin L. Brown, James F. Burke, Timothy P. Hofer, Alexander Tsodikov, Ellen G. Hoeffner, A.M. Fendrick, Eric E. Adelman, Lewis B. Morgenstern
First published October 28, 2015, DOI: https://doi.org/10.1212/WNL.0000000000002141
Full PDF
Citation
Permissions

Make Comment

See Comments

Downloads
1182

Share

Article Information

vol. 85 no. 21 1869-1878
DOI: 
https://doi.org/10.1212/WNL.0000000000002141
PubMed: 
26511453
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received October 16, 2014
  • Accepted in final form June 29, 2015
  • First Published October 28, 2015.

Article Versions

Copyright & Usage: 
© 2015 American Academy of Neurology

Author Disclosures

    1. Kevin A. Kerber, MD,
    2. William J. Meurer, MD,
    3. Devin L. Brown, MD,
    4. James F. Burke, MD,
    5. Timothy P. Hofer, MD,
    6. Alexander Tsodikov, PhD,
    7. Ellen G. Hoeffner, MD,
    8. A.M. Fendrick, MD,
    9. Eric E. Adelman, MD and
    10. Lewis B. Morgenstern, MD
  1. Kevin A. Kerber, MD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. (1) Elsevier Inc, author honoraria (2) American Academy of Neurology, travel funding

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. (1) Clinical Neurophysiology of the Vestibular System, 4th edition, Oxford University Press, 2011

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. (1) American Academy of Neurology (2) University of California San Francisco (including work on a project funded by AstraZeneca) (3) Best Doctors, Inc

    Speakers' Bureaus:

    1. NONE

    Other activities:

    1. (1) NIH, loan repayment award. (2) American Academy of Neurology, speaker honoraria (3) University of Southern California, speaker honoraria

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) NIH/NIDCD R01DC012760, principal investigator, 2013- 2018 (2) AHRQ R18HS022258, principal investigator, 2014-2019 (3) AHRQ R18 HS017690, principal investigator, 2009-2013 (4) NIH U01DC013778-01A1, site investigator, 2014-2019

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. (1) Phil Pearsons, MD, JD., review of legal records, 2013 (2) National Medical Consultants, review of legal records, 2014

  2. William J. Meurer, MD,
    3. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Society of Academic Emergency Medicine, Compensated Methodology Statistics Reviewer, 2009-2014

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) Agency for Healthcare Quality and Research #R18HS017690, CO-Investigator 2009-2013 (2) National Institute of Neurological Disorders and Stroke / Food and Drug Administration #U01NS073476, Co- Investigator 2012-present (3) National Institute of Neurological Disorders and Stroke U01NS056975, Co-Investigator 2010-2013 (4) National Institute of Deafness and Communication Disorders, R01 DC012760, Principal Investigator (Multiple) 2013-present (5) Agency for Healthcare Quality and Research, R18HS022258, Co- Investigator, 2014-present (6) National Institute of Deafness and Communication Disorders, U01 DC013778, Site CoInvestigator 2014-present (7) National Institute of Neurological Disorders and Stroke R25 NS088248, Principal-Investigator 2014-present

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Devin L. Brown, MD,
    4. Scientific Advisory Boards:

    1. Steering Committee Member, Northern Manhattan Initiative for Minority involvement in Clinical Trials (NIMICT) (U24MD006961); StrokeNet Trial Recruitment and Retention for Under-represented Minorities and Ethnicities Advisory Committee (NINDS)

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. Wayne State University, honorarium for talk.

    Editorial Boards:

    1. (1) Neurology, editorial board member, 2008-present (2) Stroke, editorial board member, 2011-June 2015

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. CVR Global, Inc, 12/12/08 ? 06/30/10, research grant.

    Research Support, Government Entities:

    1. AHRQ, R18 HS017690, Co-I, 12/1/09 ? 11/30/13 NINDS, R01 NS062675, PI, 06/15/09 ? 05/31/14 NHLBI, R01 HL098065, PI, 06/01/10 ? 05/31/14 NINDS, R01 NS070941, PI, 05/01/11 - 04/30/16 NIH, R01 DC012760, Co-I, 08/1/13 - 07/31/18 NINDS, U10NS086526, PI, 09/01/13 - 07/01/18 NHLBI, R01HL123379, PI, 4/17/15 - 03/31/19

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. (1) Blue Cross Blue Shield of Michigan Foundation, (2) Michigan Department of Community Health

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. James F. Burke, MD,
    5. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. American Academy of Neurology, Continuum Article

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other activities:

    1. Dr. Burke has received compensation from Astra Zeneca for his role as an adjudicator in the SOCRATES trial.

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. Dr. Burke is funded by NIH K08 NS082597 and R01 MD008879.

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. Dr. Burke has reviewed case materials in a medical malpractice defense case.

  5. Timothy P. Hofer, MD,
    6. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. Project Number: P01CA163233-01A1 Source: NIH P01 (S Katz) Title of Project: The Challenge of Individualizing Treatments for Patients with Breast Cancer Dates of Project: 9/1/12-8/31/17 Project Number: R01-HS-018334-05 (McMahon) Source: AHRQ Title of Project: Models of hospital-acquired conditions and readmission: defining at-risk patients Dates of Project: 9/1/13-8/31/16 Project Number: P30DK092926-01 (W Herman) Source: NIH/NIDDK Title of Project: Michigan Center for Diabetes Translational Research (P30) Dates of Project: 9/6/11-6/30/16 Project Number: 1-R01-HS-022305-01-A1 (Manojlovich) Source: AHRQ Title of Project: The Effect of Health Information Technology on Healthcare Provider Communication Dates of Project: 09/30/2014-09/29/2018 Project Number: K08 HS19767-01 (J Meddings) Source: AHRQ Title of Project: Targeting Hospital-Acquired Complications: Impact on the Care of Complex Patients Dates of Project: 9/30/10-7/31/15 Project Number: DIB 98-001 (C Richardson) Source: Department of Veterans Affairs Health Services Research & Development Title of Project: Quality Enhancement Research Initiative ? Diabetes Mellitus (QUERI-DM) Dates of Project: 10/01/04-09/30/15 Project Number: CIN 13-408 (EA Kerr) Source: Department of Veterans Affairs Health Services Research & Development Title of Project: VA Center for Clinical Management Research Dates of Project: 10/01/13-09/30/18 Project Number: IIR 13-079 (Iwashyna) Source: VA Title of Project: Recovery after In-Hospital Cardiac Arrest: Late Outcomes & Utilization (ReSCU) Dates of Project: 08/01/2014-07/31/2017 Project Number: SDR 10-180 (K Langa) Source: Department of Veterans Affairs Title of Project: VA-HRS Data Linkage Project Dates of Project: 2/1/12-9/30/15 Project Number: EPID-011-11S (S Saint) Source: Department of Veterans Affairs Clinical Science Research & Development Title of Project: Predictors of Hospital-Acquired Urinary Tract-Related Bloodstream Infection in VA Project Number: IIR 12-116 (S Hawley) Source: VA Healthcare System (HSR&D) Title of Project: Optimizing Veteran-Centered Prostate Cancer Survivorship Care Dates of Project: 4/1/13-3/31/17 Project Number: IIR 11-088 (Hayward) Source: VA-ORD Title of Project: Developing and Validating a Veterans Affairs Cardiac Risk Score Dates of Project: 9/1/12-2/28/16

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. Source: Robert Wood Johnson Title of Project: RWJ Clinical Scholars Admin Program and Scholars 2014-2016 ID#71900 Dates of Project: 7/01/14-6/30/16

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  6. Alexander Tsodikov, PhD,
    7. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH 1R01DC012760-01A1 (Kerber), Biostatistician

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  7. Ellen G. Hoeffner, MD,
    8. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. St John Hospital, Detroit, MI, speaker honoraria

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  8. A.M. Fendrick, MD,
    9. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. American Journal of Managed Care

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. Merck and Co., Pfizer Inc.

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  9. Eric E. Adelman, MD and
    10. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. (1) Honorarium from the Michigan Academy of Family Physicians for CME activity.

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. (1) Receives consulting fees from the University of California, San Francisco for work on a project funded by AstraZeneca.

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. (1) Medtronic, (2) Boston Scientific

    Research Support, Government Entities:

    1. (1) NIH, U01NS062835, co-investigator, 09/2011-08/2014. (2) AHRQ, R18HS017690, co-investigator, 01/2012-03/2013.

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  10. Lewis B. Morgenstern, MD
    11. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. AGA medical corp

    Research Support, Government Entities:

    1. NIH/NINDS [#R01 NS38916 (PI), #R01 NS050372 (Co-I),#U01 NS052510 (Co-I), #U01 NS056975 (Co-I), #U54 NS057405 (Co-I), #R01 NS062675(PI)]

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Stroke Program (K.A.K., W.J.M., D.L.B., J.F.B., E.E.A., L.B.M.) and Departments of Neurology (K.A.K., W.J.M., D.L.B., J.F.B., E.E.A., L.B.M.), Emergency Medicine (W.J.M.), Internal Medicine (T.P.H., A.M.F.), and Radiology (E.G.H.), University of Michigan Health System, Ann Arbor; and Department of Biostatistics (A.T.), University of Michigan School of Public Health, Ann Arbor.
  1. Correspondence to Dr. Kerber: kakerber{at}umich.edu
View Full Text

Article usage

Article usage: October 2015 to May 2023

AbstractFullPdfSource
Oct 2015334025Highwire
Nov 2015335953287Highwire
Dec 2015146250116Highwire
Jan 20165041345Highwire
Feb 20162181437Highwire
Mar 20162101925Highwire
Apr 2016148714Highwire
May 2016144814Highwire
Jun 201613325Highwire
Jul 201646310Highwire
Aug 20169157Highwire
Sep 201678810Highwire
Oct 20169027Highwire
Nov 20166554Highwire
Nov 20160107pmc
Dec 20167243Highwire
Dec 201603322pmc
Jan 20179556Highwire
Jan 201702219pmc
Feb 20177517Highwire
Feb 201701817pmc
Mar 201711522Highwire
Mar 201702219pmc
Apr 20179423Highwire
Apr 2017162321pmc
May 201713700Highwire
May 2017162325pmc
Jun 20177432Highwire
Jun 2017122425pmc
Jul 20176331Highwire
Jul 201791616pmc
Aug 20175434Highwire
Aug 2017142021pmc
Sep 20175011Highwire
Sep 201782126pmc
Oct 20177603Highwire
Oct 2017113356pmc
Nov 20175921Highwire
Nov 2017183140pmc
Dec 20174843Highwire
Jan 20187045Highwire
Feb 20188212Highwire
Mar 20188122Highwire
Apr 20183111Highwire
Apr 2018142727pmc
May 20188520Highwire
Jun 20186161Highwire
Jun 2018133029pmc
Jul 20185701Highwire
Aug 20186100Highwire
Aug 2018185963pmc
Sep 20185601Highwire
Oct 20186811Highwire
Nov 20186641Highwire
Dec 20186720Highwire
Jan 20193820Highwire
Feb 20195030Highwire
Mar 20195583Highwire
Apr 20196145Highwire
May 20195611Highwire
Jun 20195654Highwire
Jul 20192421Highwire
Aug 20194611Highwire
Sep 20194332Highwire
Oct 20193820Highwire
Nov 20194322Highwire
Dec 20195601Highwire
Jan 20203343Highwire
Feb 20205820Highwire
Mar 20205011Highwire
Apr 20205054Highwire
May 20205633Highwire
Jun 20203910Highwire
Jul 20205820Highwire
Aug 20205872Highwire
Sep 20206442Highwire
Oct 20204321Highwire
Nov 20203911Highwire
Dec 20204000Highwire
Jan 20214342Highwire
Feb 20217950Highwire
Mar 20214452Highwire
Apr 20215852Highwire
May 20215741Highwire
Jun 202162102Highwire
Jul 20216230Highwire
Aug 20218472Highwire
Sep 20212613Highwire
Oct 202113342Highwire
Nov 20217751Highwire
Dec 20216861Highwire
Jan 20226551Highwire
Feb 20227411Highwire
Mar 202211520Highwire
Apr 20225232Highwire
May 2022108149Highwire
Jun 202210372Highwire
Jul 202254133Highwire
Aug 20226340Highwire
Sep 202210045Highwire
Oct 20226322Highwire
Nov 202210920Highwire
Dec 20227453Highwire
Jan 20237653Highwire
Feb 20236510Highwire
Mar 20234621Highwire
Apr 20234722Highwire
May 20234433Highwire

Cited By...

Letters: Rapid online correspondence

No comments have been published for this article.
Comment

REQUIREMENTS

You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.

Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.

If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.

Submission specifications:

  • Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
  • Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
  • Submit only on articles published within 6 months of issue date.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Publishing Agreement Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top
Advertisement

Topics Discussed

Alert Me

Recommended articles