Skip to main content
Advertisement
  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Education
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Online Sections
    • Neurology Video Journal Club
    • Diversity, Equity, & Inclusion (DEI)
    • Innovations in Care Delivery
    • Practice Buzz
    • Practice Current
    • Residents & Fellows
    • Without Borders
  • Collections
    • COVID-19
    • Disputes & Debates
    • Health Disparities
    • Infographics
    • Neurology Future Forecasting Series
    • Null Hypothesis
    • Patient Pages
    • Topics A-Z
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit New Manuscript
    • Submit Revised Manuscript
    • Author Center

Advanced Search

Main menu

  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Education
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Online Sections
    • Neurology Video Journal Club
    • Diversity, Equity, & Inclusion (DEI)
    • Innovations in Care Delivery
    • Practice Buzz
    • Practice Current
    • Residents & Fellows
    • Without Borders
  • Collections
    • COVID-19
    • Disputes & Debates
    • Health Disparities
    • Infographics
    • Neurology Future Forecasting Series
    • Null Hypothesis
    • Patient Pages
    • Topics A-Z
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit New Manuscript
    • Submit Revised Manuscript
    • Author Center
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Neurology Video Journal Club
  • Residents & Fellows

User menu

  • Subscribe
  • My Alerts
  • Log in

Search

  • Advanced search
Neurology
Home
The most widely read and highly cited peer-reviewed neurology journal
  • Subscribe
  • My Alerts
  • Log in
Site Logo
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Neurology Video Journal Club
  • Residents & Fellows

Share

March 29, 2016; 86 (13) Article

Low-frequency and common genetic variation in ischemic stroke

The METASTROKE collaboration

Rainer Malik, Matthew Traylor, Sara L. Pulit, Steve Bevan, Jemma C. Hopewell, Elizabeth G. Holliday, Wei Zhao, Patricia Abrantes, Philippe Amouyel, John R. Attia, Thomas W.K. Battey, Klaus Berger, Giorgio B. Boncoraglio, Ganesh Chauhan, Yu-Ching Cheng, Wei-Min Chen, Robert Clarke, Ioana Cotlarciuc, Stephanie Debette, Guido J. Falcone, Jose M. Ferro, Dale M. Gamble, Andreea Ilinca, Steven J. Kittner, Christina E. Kourkoulis, Robin Lemmens, Christopher R. Levi, Peter Lichtner, Arne Lindgren, Jingmin Liu, James F. Meschia, Braxton D. Mitchell, Sofia A. Oliveira, Joana Pera, Alex P. Reiner, Peter M. Rothwell, Pankaj Sharma, Agnieszka Slowik, Cathie L.M. Sudlow, Turgut Tatlisumak, Vincent Thijs, Astrid M. Vicente, Daniel Woo, Sudha Seshadri, Danish Saleheen, Jonathan Rosand, Hugh S. Markus, Bradford B. Worrall, Martin Dichgans, For the ISGC Analysis Group, For the METASTROKE collaboration, The Wellcome Trust Case Control Consortium 2 (WTCCC2), The NINDS Stroke Genetics Network (SiGN)
First published March 2, 2016, DOI: https://doi.org/10.1212/WNL.0000000000002528
Rainer Malik
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Matthew Traylor
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sara L. Pulit
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Steve Bevan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jemma C. Hopewell
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elizabeth G. Holliday
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wei Zhao
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Patricia Abrantes
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Philippe Amouyel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John R. Attia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas W.K. Battey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Klaus Berger
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Giorgio B. Boncoraglio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ganesh Chauhan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yu-Ching Cheng
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wei-Min Chen
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert Clarke
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ioana Cotlarciuc
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stephanie Debette
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Guido J. Falcone
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jose M. Ferro
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dale M. Gamble
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andreea Ilinca
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Steven J. Kittner
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christina E. Kourkoulis
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robin Lemmens
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christopher R. Levi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter Lichtner
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Arne Lindgren
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jingmin Liu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James F. Meschia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Braxton D. Mitchell
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sofia A. Oliveira
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joana Pera
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alex P. Reiner
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter M. Rothwell
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pankaj Sharma
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Agnieszka Slowik
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cathie L.M. Sudlow
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Turgut Tatlisumak
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vincent Thijs
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Astrid M. Vicente
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel Woo
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sudha Seshadri
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Danish Saleheen
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jonathan Rosand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hugh S. Markus
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bradford B. Worrall
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martin Dichgans
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Full PDF
Citation
Low-frequency and common genetic variation in ischemic stroke
The METASTROKE collaboration
Rainer Malik, Matthew Traylor, Sara L. Pulit, Steve Bevan, Jemma C. Hopewell, Elizabeth G. Holliday, Wei Zhao, Patricia Abrantes, Philippe Amouyel, John R. Attia, Thomas W.K. Battey, Klaus Berger, Giorgio B. Boncoraglio, Ganesh Chauhan, Yu-Ching Cheng, Wei-Min Chen, Robert Clarke, Ioana Cotlarciuc, Stephanie Debette, Guido J. Falcone, Jose M. Ferro, Dale M. Gamble, Andreea Ilinca, Steven J. Kittner, Christina E. Kourkoulis, Robin Lemmens, Christopher R. Levi, Peter Lichtner, Arne Lindgren, Jingmin Liu, James F. Meschia, Braxton D. Mitchell, Sofia A. Oliveira, Joana Pera, Alex P. Reiner, Peter M. Rothwell, Pankaj Sharma, Agnieszka Slowik, Cathie L.M. Sudlow, Turgut Tatlisumak, Vincent Thijs, Astrid M. Vicente, Daniel Woo, Sudha Seshadri, Danish Saleheen, Jonathan Rosand, Hugh S. Markus, Bradford B. Worrall, Martin Dichgans, For the ISGC Analysis Group, For the METASTROKE collaboration, The Wellcome Trust Case Control Consortium 2 (WTCCC2), The NINDS Stroke Genetics Network (SiGN)
Neurology Mar 2016, 86 (13) 1217-1226; DOI: 10.1212/WNL.0000000000002528

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Permissions

Make Comment

See Comments

Downloads
949

Share

This article has a correction. Please see:

  • Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration - September 20, 2016
  • Article
  • Figures & Data
  • Info & Disclosures
Loading

AAN Members

We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.

Google Safari Microsoft Edge Firefox

Click here to login

AAN Non-Member Subscribers

Click here to login

Purchase access

For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)

Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here 

Purchase
Individual access to articles is available through the Add to Cart option on the article page.  Access for 1 day (from the computer you are currently using) is US$ 39.00.  Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means.  The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use.  Distributing copies (electronic or otherwise) of the article is not allowed.

Letters: Rapid online correspondence

No comments have been published for this article.
Comment

REQUIREMENTS

If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org

Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.

If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.

Submission specifications:

  • Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
  • Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
  • Submit only on articles published within 6 months of issue date.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Publishing Agreement Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top
  • Article
    • Abstract
    • GLOSSARY
    • METHODS
    • RESULTS
    • DISCUSSION
    • AUTHOR AFFILIATIONS
    • AUTHOR CONTRIBUTIONS
    • STUDY FUNDING
    • DISCLOSURE
    • ACKNOWLEDGMENT
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Disclosures
Advertisement

Use of Whole-Genome Sequencing for Mitochondrial Disease Diagnosis

Dr. Robert Pitceathly and Dr. William Macken

► Watch

Related Articles

  • Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration

Topics Discussed

  • All Genetics
  • All Cerebrovascular disease/Stroke
  • Association studies in genetics

Alert Me

  • Alert me when eletters are published

Recommended articles

  • Abstracts
    Proceedings of the 25th International Stroke Genetics Consortium Workshop: Cambridge, UK
    Jemma C. Hopewell, Matthew Traylor, Hugh S. Markus et al.
    Neurology: Genetics, May 21, 2020
  • Article
    COL4A2 is associated with lacunar ischemic stroke and deep ICH
    Meta-analyses among 21,500 cases and 40,600 controls
    Kristiina Rannikmäe, Vhinoth Sivakumaran, Henry Millar et al.
    Neurology, September 27, 2017
  • Abstracts
    20th Workshop of the International Stroke Genetics Consortium, November 3–4, 2016, Milan, Italy
    et al.
    Neurology: Genetics, March 30, 2017
  • Abstracts
    Proceedings of the 24th International Stroke Genetics Consortium Workshop: Washington, DC, USA
    Paul A. Nyquist, John W. Cole et al.
    Neurology: Genetics, April 08, 2019
Neurology: 100 (12)

Articles

  • Ahead of Print
  • Current Issue
  • Past Issues
  • Popular Articles
  • Translations

About

  • About the Journals
  • Ethics Policies
  • Editors & Editorial Board
  • Contact Us
  • Advertise

Submit

  • Author Center
  • Submit a Manuscript
  • Information for Reviewers
  • AAN Guidelines
  • Permissions

Subscribers

  • Subscribe
  • Activate a Subscription
  • Sign up for eAlerts
  • RSS Feed
Site Logo
  • Visit neurology Template on Facebook
  • Follow neurology Template on Twitter
  • Visit Neurology on YouTube
  • Neurology
  • Neurology: Clinical Practice
  • Neurology: Education
  • Neurology: Genetics
  • Neurology: Neuroimmunology & Neuroinflammation
  • AAN.com
  • AANnews
  • Continuum
  • Brain & Life
  • Neurology Today

Wolters Kluwer Logo

Neurology | Print ISSN:0028-3878
Online ISSN:1526-632X

© 2023 American Academy of Neurology

  • Privacy Policy
  • Feedback
  • Advertise