Health-related quality of life in multiple sclerosis
Direct and indirect effects of comorbidity
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Article Information
- Received May 27, 2015
- Accepted in final form January 5, 2016
- First Published March 9, 2016.
Article Versions
- Previous version (March 9, 2016 - 13:00).
- You are viewing the most recent version of this article.
Author Disclosures
- Lindsay I. Berrigan, PhD,
- John D. Fisk, PhD,
- Scott B. Patten, MD, PhD,
- Helen Tremlett, PhD,
- Christina Wolfson, PhD,
- Sharon Warren, PhD,
- Kirsten M. Fiest, PhD,
- Kyla A. McKay, BSc,
- Ruth Ann Marrie, MD, PhD;
- For the CIHR Team in the Epidemiology and Impact of Comorbidity on Multiple Sclerosis (ECoMS)
- Lindsay I. Berrigan, PhD,
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(1)Multiple Sclerosis Society of Canada, Postdoctoral Fellowship
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- John D. Fisk, PhD,
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EMD Serono, Travel expenses and $1500 honourarium for workshop participation (June 2014).
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(1)CIHR operating grant, ?Early and preclinical diagnosis of Parkinson's disease using olfactory testing and Diffusion Tensor Imaging of olfactory bulb and substantia nigra.? 2012-2017, Co-investigator. (2)CIHR Team Grant, ?Defining the burden and managing the effects of psychiatric comorbidity in chronic immunoinflammatory disease.? 07/2014-06/2019,Co- investigator. (3)CIHR ? Emerging Team Grant: “Co-morbidity of brain disorders and other health problems” 2010?2015, Co- investigator. (4) CIHR operating grant, ?Epidemiology of cognitive dynamics in older adults? 2010 -2015, Co-investigator (5) CIHR catalyst grant (Exploring ADNI and other Neuroimaging Databases to benefit the early detection of Alzheimer's Disease and Related Dementias),?Alternative FDG-PET relative standardized uptake value metrics for the assessment of early metabolic biomarkers of Alzheimer's disease.? 2014-2016, Co-investigator. (6) CIHR catalyst grant (Exploring ADNI and other Neuroimaging Databases to benefit the early detection of Alzheimer's Disease and Related Dementias)?Pre- symptomatic biomarkers for Alzheimer?s disease: Structural and functional changes in white matter and brain connectivity.? 2014-2016, Co-investigator.
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National MS Society operating Grant ?Prodromal Multiple Sclerosis: The PrOMS Study?. 2016 - 2018, Co- investigator.
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Fatigue Impact Scale and Daily Fatigue Impact Scale, Licensing and Distribution agreement with MAPI Research Trust.
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- Scott B. Patten, MD, PhD,
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speaker honoraria from Teva and Lundbeck
(1) Canadian Journal of Psychiatry, Editor-in-Chief, 2014-present. (2) Chronic Diseases in Canada, Editorial Advisory Board Member, 2009-present. (3) Clinical Practice and Epidemiology in Mental Health, Editorial Advisory Board Member, 2010-present.
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Epidemiology for Canadian Students. Brush Education, 2015.
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honoraria for reviewing investigator-initiated grant applications submitted to Lundbeck and Pfizer
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(1) Canadian Institutes for Health Research, MOP-89816, P.I. 2008-2011 and MOP-130415, P.I. 2013-2015. (2) Hotchkiss Brain Institute. Depression in the Community, 2013-2016. (4) I receive salary support from Alberta Innovates, Health Solutions as a Senior Health Scholar.
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Alberta Collaborative Research Grants Initiative.
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- Helen Tremlett, PhD,
All non-profit: ? National US surveillance system for MS. 2013-present. Invited by the US National MS Society to form an advisory group to enable the development of a national surveillance system capable of tracking the incidence and prevalence of MS. Monthly teleconferences; one face-to-face meeting: Atlanta, Georgia (March 2014) Status: Bipartisan legislation introduced to Congress - ?Advancing Research for Neurological Diseases Act, H.R. 292.?to guide the Centers for Disease Control and Prevention in tracking the incidence and prevalence of neurological diseases, including Multiple Sclerosis and Parkinson?s disease [13th-Jan-2015; http://burgess.house.gov/blog/? postid=397459] ? Scientific Advisory Board member, ?A randomized controlled trial of vitamin D in multiple sclerosis.?Investigator initiated study funded by the US National MS Society. PI: (Dr Ellen Mowry). Study location: USA: University of California, San Francisco; Johns Hopkins University; University of Pennsylvania; Washington University St. Louis, Virginia Mason Medical Center; Oregon Health & Science University; Mt. Sinai School of Medicine; Cleveland Clinic; University of Vermont; Yale University (October 2012-2013) ? Multiple Sclerosis International Federation advisory group for the ?Atlas of MS? 2013 update. Website: http://www.atlasofms.org/ This international, interactive on-line resource is well used by the MS community and endorsed by the World health Organization (http://www.who.int/mental_health/neurology/Atlas_MS_WEB.pdf ). Established in 2006, it needs updating, but requires input from the MS community. Personal role: identifying key experts in MS required to populate the website; completing Canada?s section on epidemiology & MS; generating interest in the website; presented results at international conference (Copenhagen Oct/ 2013). Sept 2012-Dec 2013
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Helen Tremlett has received funding from the Multiple Sclerosis Society of Canada (Don Paty Career Development Award); is the Michael Smith Foundation for Health Research Scholar Award and the Canada Research Chair for Neuroepidemiology and Multiple Sclerosis. She has received: research support from the National Multiple Sclerosis Society, the Canadian Institutes of Health Research, and the UK MS Trust; speaker honoraria and/or travel expenses to attend conferences from the Consortium of MS Centres (2013), the National MS Society (2012, 2014), Bayer Pharmaceuticals (2010), Teva Pharmaceuticals (2011), ECTRIMS (2011, 2012, 2013, 2014, 2015), UK MS Trust (2011), the Chesapeake Health Education Program, US Veterans Affairs (2012), Novartis Canada (2012), Biogen Idec (2014), American Academy of Neurology (2013, 2014, 2015). Unless otherwise stated, all speaker honoraria are either donated to an MS charity or to an unrestricted grant for use by her research group.
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Canadian Institutes of Health Research [#190898 (PI) and #MOP-82738 (PI) and MOP-119393 (PI) and MOP-106607 (PI)]; the US National Multiple Sclerosis Society (Operating grants: 2006-09; 2009-12; 2012-15; 2014-17), the Multiple Sclerosis Society of Canada (2015-18; EGID #2624 (PI)) the Multiple Sclerosis Society of Canada (Don Paty Career Development Award, 2004-2014), and a Michael Smith Foundation for Health Research Scholar Award (2006- 2014); Canada Research Chair in Neuroepidemiology and Multiple Sclerosis
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- Christina Wolfson, PhD,
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Novartis (speaker honorarium)
Journal of Military, Veteran and Family Health. Member of Editorial Board. 2014 to present.
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Canadian Institutes of Health Research. Canada Foundation for Innovation. National Multiple Sclerosis Society.
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Multiple Sclerosis Society of Canada
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- Sharon Warren, PhD,
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CIHR
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Expert opinion paper on trauma and MS on behalf of legal firm
- Kirsten M. Fiest, PhD,
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- Kyla A. McKay, BSc,
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MS Society of Canada Alistair M Fraser Masters Studentship Award
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- Ruth Ann Marrie, MD, PhD;
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Neurology, Editorial Board Multiple Sclerosis Journal, Editorial Board
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Received support as site Principal Investigator for clinical trials from Sanofi-Aventis (2007-2014)
Received support as principal investigator from the Canadian Institutes of Health Research (2010-2019), the Public Health Agency of Canada (2010-2013), and Research Manitoba (2014-2019).
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Received support as principal investigator from Multiple Sclerosis Society of Canada (2009-2016) and the National Multiple Sclerosis Society (2013-2015), and as co-principal investigator from Multiple Sclerosis Scientific Foundation (2009-2015). Received support from Consortium of Multiple Sclerosis Centers (2004-2009, 2011-2014). Rx & D Health Research Foundation
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- For the CIHR Team in the Epidemiology and Impact of Comorbidity on Multiple Sclerosis (ECoMS)
- From the Department of Psychology (L.I.B.), St. Francis Xavier University, Antigonish; Department of Psychiatry (L.I.B., J.D.F.), Department of Medicine (J.D.F.), Dalhousie University, Halifax; Departments of Psychiatry and Community Health Sciences (S.B.P.), Cumming School of Medicine, University of Calgary; Division of Neurology, Faculty of Medicine (H.T., K.A.M.), University of British Columbia, Vancouver; Departments of Epidemiology & Biostatistics, Occupational Health, & Medicine (C.W.), McGill University, Montreal; Faculty of Rehabilitation Medicine (S.W.), University of Alberta, Edmonton; and Departments of Internal Medicine (K.M.F., R.A.M.) and Community Health Sciences (R.A.M.), College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
- Correspondence to Dr. Berrigan: lberriga{at}stfx.ca
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