Skip to main content
Advertisement
  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Specialty Sites
    • COVID-19
    • Practice Current
    • Practice Buzz
    • Without Borders
    • Equity, Diversity and Inclusion
    • Innovations in Care Delivery
  • Collections
    • Topics A-Z
    • Residents & Fellows
    • Infographics
    • Patient Pages
    • Null Hypothesis
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center

Advanced Search

Main menu

  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Specialty Sites
    • COVID-19
    • Practice Current
    • Practice Buzz
    • Without Borders
    • Equity, Diversity and Inclusion
    • Innovations in Care Delivery
  • Collections
    • Topics A-Z
    • Residents & Fellows
    • Infographics
    • Patient Pages
    • Null Hypothesis
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Residents & Fellows

User menu

  • Subscribe
  • My Alerts
  • Log in

Search

  • Advanced search
Neurology
Home
The most widely read and highly cited peer-reviewed neurology journal
  • Subscribe
  • My Alerts
  • Log in
Site Logo
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Residents & Fellows

Share

April 05, 2016; 86 (16 Supplement) April 16, 2016

PRELIMINARY DATA ON DRIVING ABILITY IN CHARCOT MARIE TOOTH 1A (CMT 1A) PATIENTS (P1.141)

Nivedita Jerath, Shawna Feely, Jeffrey Dawson, Nazan Aksan, Matthew Rizzo, Michael Shy
First published April 4, 2016,
Nivedita Jerath
1University of Iowa Iowa City IA United States
2University of Iowa Iowa City IA United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shawna Feely
1University of Iowa Iowa City IA United States
2University of Iowa Iowa City IA United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jeffrey Dawson
3Biostatistics University of Iowa Iowa City IA United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nazan Aksan
1University of Iowa Iowa City IA United States
2University of Iowa Iowa City IA United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Matthew Rizzo
4University of Nebraska Medical Center Omaha NE United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Shy
1University of Iowa Iowa City IA United States
2University of Iowa Iowa City IA United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Citation
PRELIMINARY DATA ON DRIVING ABILITY IN CHARCOT MARIE TOOTH 1A (CMT 1A) PATIENTS (P1.141)
Nivedita Jerath, Shawna Feely, Jeffrey Dawson, Nazan Aksan, Matthew Rizzo, Michael Shy
Neurology Apr 2016, 86 (16 Supplement) P1.141;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Permissions

Make Comment

See Comments

Downloads
0

Share

  • Article
  • Info & Disclosures
Loading

Abstract

Objective: To determine driving ability in those with CMT1A. Background: Driving is a complex task requiring rapid responses, which can be impaired by weakness and sensory loss in those with peripheral neuropathies (PN). CMT1A subjects provide an ideal cohort for a study in how PN affects driver performance and safety. Methods: The following study draws from our registry of patients with CMT1A who have various levels of impairment indexed by the CMT Neuropathy Score (CMTNSv2). To evaluate driving abilities in CMT1A, sixteen participants with CMT1A and eight normal controls were tested using driving simulation scenarios implemented on the Simulator for Interdisciplinary Research in Ergonomics and Neuroscience (SIREN), a high performance driving simulator (a four-door 1994 GM Saturn SL2). SAS (statistical analysis software) was used to analyze data. Results: CMT1A patients reported on average two times more motor vehicle accidents (MVA’s) than controls. CMT drivers had double the rates of lane departures and lane crossings compared to controls (p=0.0006 and p=0.0040, respectively). Lane control variability was very similar in the two groups (p=0.7718), while steering wheel variability was about 1/3rd higher for CMT drivers, though not statistically significant (p=0.2266). Similarly, although collision rates were almost double in the CMT group compared to controls, this was not significant (p=0.1990). None of the five measures of driving were significantly associated with the CMTNSv2. Conclusion: Our preliminary data suggest that CMT1A patients self-report more MVA’s and make more lane deviation safety errors on a variety of driving scenarios and tasks in SIREN compared to controls. We will continue to acquire data on driving safety in CMT1A patients, which will provide insight on improving driving safety in patients with PN. Our next step will be to implement hand controls and determine if they reduce driving errors in those with PN.

Disclosure: Dr. Jerath has nothing to disclose. Dr. Feely has nothing to disclose. Dr. Dawson has nothing to disclose. Dr. Aksan has nothing to disclose. Dr. Rizzo has received research support from Nissan Auto. Dr. Shy has nothing to disclose.

Saturday, April 16 2016, 8:30 am-7:00 pm

  • Copyright © 2016 by AAN Enterprises, Inc.

Disputes & Debates: Rapid online correspondence

No comments have been published for this article.
Comment

NOTE: All authors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.

  • Stay timely. Submit only on articles published within the last 8 weeks.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • 200 words maximum.
  • 5 references maximum. Reference 1 must be the article on which you are commenting.
  • 5 authors maximum. Exception: replies can include all original authors of the article.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Disputes & Debates Submission Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top
  • Article
  • Info & Disclosures
Advertisement

Related Articles

  • No related articles found.

Alert Me

  • Alert me when eletters are published
Neurology: 96 (2)

Articles

  • Ahead of Print
  • Current Issue
  • Past Issues
  • Popular Articles
  • Translations

About

  • About the Journals
  • Ethics Policies
  • Editors & Editorial Board
  • Contact Us
  • Advertise

Submit

  • Author Center
  • Submit a Manuscript
  • Information for Reviewers
  • AAN Guidelines
  • Permissions

Subscribers

  • Subscribe
  • Activate a Subscription
  • Sign up for eAlerts
  • RSS Feed
Site Logo
  • Visit neurology Template on Facebook
  • Follow neurology Template on Twitter
  • Visit Neurology on YouTube
  • Neurology
  • Neurology: Clinical Practice
  • Neurology: Genetics
  • Neurology: Neuroimmunology & Neuroinflammation
  • AAN.com
  • AANnews
  • Continuum
  • Brain & Life
  • Neurology Today

Wolters Kluwer Logo

Neurology | Print ISSN:0028-3878
Online ISSN:1526-632X

© 2021 American Academy of Neurology

  • Privacy Policy
  • Feedback
  • Advertise