Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study
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In the article “Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study” by M.D. Zwan et al. (Neurology 2016;86:50–58), concordance was incorrectly defined in the Methods section. The correct definition is “the proportion of individuals with an identical classification of both biomarkers, e.g., normal CSF biomarkers (not Alzheimer-like) (either Aβ42 alone or Aβ42/tau) and normal (negative) amyloid-PET or abnormal (Alzheimer-like) CSF biomarkers (either Aβ42 alone or Aβ42/tau) and abnormal (positive) amyloid-PET.” In addition, the patient numbers described in the Results section under “Concordance between CSF Aβ42/tau ratio and amyloid-PET” are incorrect and should have been 140, 218, 39, and 17, respectively, as shown in table 5. The authors regret the errors.
- © 2016 American Academy of Neurology
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