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February 09, 2016; 86 (6) Views & Reviews

Accuracy of clinical diagnosis of Parkinson disease

A systematic review and meta-analysis

Giovanni Rizzo, Massimiliano Copetti, Simona Arcuti, Davide Martino, Andrea Fontana, Giancarlo Logroscino
First published January 13, 2016, DOI: https://doi.org/10.1212/WNL.0000000000002350
Giovanni Rizzo
From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
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Massimiliano Copetti
From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
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Simona Arcuti
From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
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Davide Martino
From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
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Andrea Fontana
From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
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Giancarlo Logroscino
From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
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Full PDF
Citation
Accuracy of clinical diagnosis of Parkinson disease
A systematic review and meta-analysis
Giovanni Rizzo, Massimiliano Copetti, Simona Arcuti, Davide Martino, Andrea Fontana, Giancarlo Logroscino
Neurology Feb 2016, 86 (6) 566-576; DOI: 10.1212/WNL.0000000000002350

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Article Information

vol. 86 no. 6 566-576
DOI: 
https://doi.org/10.1212/WNL.0000000000002350
PubMed: 
26764028

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received March 5, 2015
  • Accepted in final form October 16, 2015
  • First Published January 13, 2016.

Article Versions

  • Previous version (January 13, 2016 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Giovanni Rizzo, MD,
    2. Massimiliano Copetti, PhD,
    3. Simona Arcuti, PhD,
    4. Davide Martino, MD,
    5. Andrea Fontana, MSc and
    6. Giancarlo Logroscino, MD
  1. Giovanni Rizzo, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Massimiliano Copetti, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Simona Arcuti, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Davide Martino, MD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Nature Parkinson's Journal, Associate Editor, 2014-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. Tourette syndrome, Oxford University Press, 2013

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Andrea Fontana, MSc and
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Giancarlo Logroscino, MD
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. received within the last two years investigator- initiated research funding from the Amyotrophic Lateral Sclerosis Association, Italian Ministry of Health, and the Apulia Region, European Union. He has received honoraria from Pfeizer, Novartis, Glaxo and Lilly Pharmaceutical for speaking-educational engagements, and has received special funding from the Italian Ministry of University.

    Editorial Boards:
    1. Associate Editor of Neuroepidemiology since January, 1 2008

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Clinical Research in Neurology (G.R., S.A., G.L.), University of Bari, Tricase; Department of Biomedical and Neuromotor Sciences (G.R.), University of Bologna; Unit of Biostatistics (M.C., A.F.), IRCCS “Casa Sollievo della Sofferenza,” San Giovanni Rotondo, Italy; Department of Neurology (D.M.), King's College NHS Foundation Trust; Department of Neurology (D.M.), Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, London, UK; and Department of Basic Medical Science (G.L.), Neuroscience and Sense Organs, University of Bari, Italy.
  1. Correspondence to Dr. Logroscino: giancarlo.logroscino{at}uniba.it
View Full Text

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Cited By...

  • 314 Citations
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Disputes & Debates: Rapid online correspondence

  • Accuracy of clinical diagnosis of Parkinson disease
    • Kurt A. Jellinger, Director, Institute of Clinical Neurobiologykurt.jellinger@univie.ac.at
    Submitted February 25, 2016
  • Author response to Dr. Jellinger
    • Giancarlo Logroscino, Director, Department of Clinical Research in Neurology, University of Bari, Tricasegiancarlo.logroscino@uniba.it
    • G.Rizzo, M.Copetti, S.Arcuti, D.Martino, A.Fontana, G.Logroscino
    Submitted February 12, 2016
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