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September 06, 2016; 87 (10) Editorial

Does early (treatment in) BENEFIT lead to late MS benefit?

Brian C. Healy, Brian G. Weinshenker
First published August 10, 2016, DOI: https://doi.org/10.1212/WNL.0000000000003070
Brian C. Healy
From the Partners Multiple Sclerosis Center (B.C.H.), Brigham and Women's Hospital, Boston; Biostatistics Center (B.C.H.), Massachusetts General Hospital, Boston; and Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN.
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Brian G. Weinshenker
From the Partners Multiple Sclerosis Center (B.C.H.), Brigham and Women's Hospital, Boston; Biostatistics Center (B.C.H.), Massachusetts General Hospital, Boston; and Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN.
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Citation
Does early (treatment in) BENEFIT lead to late MS benefit?
Brian C. Healy, Brian G. Weinshenker
Neurology Sep 2016, 87 (10) 970-971; DOI: 10.1212/WNL.0000000000003070

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Article Information

vol. 87 no. 10 970-971
DOI: 
https://doi.org/10.1212/WNL.0000000000003070
PubMed: 
27511185

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • First Published August 10, 2016.

Article Versions

  • Previous version (August 10, 2016 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Brian C. Healy, PhD and
    2. Brian G. Weinshenker, MD
  1. Brian C. Healy, PhD and
  2. Scientific Advisory Boards:
    1. Member of Biogen Worldwide Medical Biostatistics MS Advisory Board

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Statistical Methods in Medical Research, editorial board, 2008-Present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Merck Serono, 12/2009-Present Novartis, 10/2012-9/2015 Genzyme, 8/2014-7/2015 Google Life Sciences, 9/2015-Present

    Research Support, Government Entities:
    1. NIH, 1UH2TR000890-01, Statistician, 2013-Present NIH, 1R01HL113272-02, Statistician, 2013-Present NIH, 1UL1TR001102-07, Statistician, 2013-Present

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. National Multiple Sclerosis Society

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Brian G. Weinshenker, MD
  4. Scientific Advisory Boards:
    1. (1) Novartis data safety monitoring board member (2) Biogen Idec data safety monitoring board member (3) Mitsubishi Pharmaceuticals data safety monitoring board member

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. 1. Canadian Journal of Neurological Sciences, editorial board member, 2006-present; no compensation 2. Turkish Journal of Neurology, editorial board member, 2005-present; no compensation 3. Neurology, editorial board member, 2014-present; no compensation

    Patents:
    1. 1) NMO-IgG for diagnosis of neuromyelitis optica; application 20050112116; patent issued and technology licensed to R.S.R. Ltd. and Oxford University

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Chugai Pharmaceuticals

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. (1)Medimmune Pharmaceuticals, Adjudication Committee Member

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Guthy Jackson Charitable Foundation, sponsor of research in NMO, 10/2008-09/2011

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NMO-IgG for diagnosis of neuromyelitis optica; patent issued and technology licensed to R.S.R. Ltd. and to Oxford University

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Partners Multiple Sclerosis Center (B.C.H.), Brigham and Women's Hospital, Boston; Biostatistics Center (B.C.H.), Massachusetts General Hospital, Boston; and Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN.
  1. Correspondence to Dr. Healy: bchealy{at}partners.org
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