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September 13, 2016; 87 (11) Article

Incidence of subarachnoid hemorrhage is decreasing together with decreasing smoking rates

Miikka Korja, Hanna Lehto, Seppo Juvela, Jaakko Kaprio
First published August 12, 2016, DOI: https://doi.org/10.1212/WNL.0000000000003091
Miikka Korja
From the Department of Neurosurgery (M.K., H.L.), University of Helsinki and Helsinki University Hospital; Departments of Clinical Neurosciences (S.J.) and Public Health (J.K.), University of Helsinki; Department of Health (J.K.), National Institute for Health and Welfare; and Institute for Molecular Medicine FIMM (J.K.), Helsinki, Finland.
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Hanna Lehto
From the Department of Neurosurgery (M.K., H.L.), University of Helsinki and Helsinki University Hospital; Departments of Clinical Neurosciences (S.J.) and Public Health (J.K.), University of Helsinki; Department of Health (J.K.), National Institute for Health and Welfare; and Institute for Molecular Medicine FIMM (J.K.), Helsinki, Finland.
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Seppo Juvela
From the Department of Neurosurgery (M.K., H.L.), University of Helsinki and Helsinki University Hospital; Departments of Clinical Neurosciences (S.J.) and Public Health (J.K.), University of Helsinki; Department of Health (J.K.), National Institute for Health and Welfare; and Institute for Molecular Medicine FIMM (J.K.), Helsinki, Finland.
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Jaakko Kaprio
From the Department of Neurosurgery (M.K., H.L.), University of Helsinki and Helsinki University Hospital; Departments of Clinical Neurosciences (S.J.) and Public Health (J.K.), University of Helsinki; Department of Health (J.K.), National Institute for Health and Welfare; and Institute for Molecular Medicine FIMM (J.K.), Helsinki, Finland.
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Full PDF
Citation
Incidence of subarachnoid hemorrhage is decreasing together with decreasing smoking rates
Miikka Korja, Hanna Lehto, Seppo Juvela, Jaakko Kaprio
Neurology Sep 2016, 87 (11) 1118-1123; DOI: 10.1212/WNL.0000000000003091

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Article Information

vol. 87 no. 11 1118-1123
DOI: 
https://doi.org/10.1212/WNL.0000000000003091
PubMed: 
27521438

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received December 26, 2015
  • Accepted in final form April 14, 2016
  • First Published August 12, 2016.

Article Versions

  • Previous version (August 12, 2016 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Miikka Korja, MD, PhD,
    2. Hanna Lehto, MD, PhD,
    3. Seppo Juvela, MD, PhD and
    4. Jaakko Kaprio, MD, PhD
  1. Miikka Korja, MD, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Hanna Lehto, MD, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. 1. Maire Taposen s??ti? (Maire Taponen Foundation) 1500e 2. Emil Aaltosen s??ti? (Emil Aaltonen Foundation) 5000e

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Seppo Juvela, MD, PhD and
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. 1) Associate editor: European Journal of Neurology, 2007-- ; 2) Editorial board member: Stroke, 2005--

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Jaakko Kaprio, MD, PhD
  8. Scientific Advisory Boards:
    1. D-tect project, PI professor Berit Heitmann, Copenhagen University, non-profit

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. 1) Pfizer Ltd, speaker honorarium 2012

    Editorial Boards:
    1. Addiction, associate editor, 2008 - > Nicotine and Tobacco Research, associate editor, 2010 - > Twin Research and Human Genetics, editorial board member, 2003 -> Finnish Journal of Social Medicine 2000-> Psychiatric Genetics, editorial board member 2000->

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Pfizer Ltd, Pharmacogenetics of smoking cessation, 2011-2014

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1.  Addiction program (#118555, PI) 2007-2010 Academy of Finland, Centre of Excellence in Complex Disease Genetics, J.Kaprio group 2006-2011 Academy of Finland Finnish Distinguished Professor programme, co-host for Professor Joe Terwilliger (Columbia University) 2006-2010 Academy of Finland Finnish Distinguished Professor programme, host for Professor Juni Palmgren (Karolinska Institute) 2011-2015 Academy of Finland. Genes and environmental predictors of tobacco addiction in adolescents and young adults (PI). Consortium partner Olli Raitakari, University of Turku. Co-funded with CIHR (PI Rachel Tyndale, University of Toronto) . Funded through the SKIDI-Kids Research program. 2011-2014 European Union funding EC FP6. DiOGenes. Diet, Obesity and Genes. FP6-513946. J.Kaprio PI for University of Helsinki, http://www.diogenes-eu.org/ 2005-2009 EC FP7. TORNADO. Molecular Targets Open for Regulation by the gut flora ? New Avenues for improved Diet to Optimize European health. KBBE-2007-2-2-07/222720-2 (JK PI for University of Helsinki partner, WP leader) Integrating project http://www.fp7tornado.eu/ 2009-2013 EC FP7. ENGAGE Consortium European Network for Genetic and Genomic Epidemiology. (HEALTH-F4-2007-201413). (JK PI University of Helsinki, University of Helsinki coordinator partner, JK WP leader). http://www.euengage.org/ Integrating project 2008-2012 EC FP7. GENODISC (Disc-degeneration linked pathologies: novel biomarkers and diagnostics for targeting treatment and repair). HEALTH-F2-2008-201626. 1.3.08-28.2.13. J.Kaprio PI for Helsinki partner and WP leader. (http://www.physiol.ox.ac.uk/genodisc/index.html) 2008-2013 EC FP7 I.Family. Determinants of eating behaviour in European children, adolescents and their parents-KBBE-2010-4. 2012-2017. J. Kaprio PI for University of Helsinki partner. 2012-2017 US NIH funding U.S. -P.H.S. (# DA-12584, yrs 6-10). Nicotine addiction genetics. Co-PI J.Kaprio. Finnish subcontract 2008-2012 U.S. -P.H.S. (# AA-12502) FinnTwin12 studies of alcohol use. Co-PI J.Kaprio. Finnish subcontract 2005-2010 U.S. -P.H.S. (# AA-15416, PI DM Dick) Gene-environment interactions in adolescent alcohol use. J.Kaprio Co-Investigator, 2005-2010 U.S.-P.H.S. (#AA-15416, PI DM Dick, Virginia Commonwealth University), supplemental award for genotyping 2009-2011 U.S.-P-H.S (# HL104125, Xiaoling Wang, Medical College of Georgia. A genome-wide methylation study on essential hypertension. (local PI J Kaprio) 2011-2016

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Neurosurgery (M.K., H.L.), University of Helsinki and Helsinki University Hospital; Departments of Clinical Neurosciences (S.J.) and Public Health (J.K.), University of Helsinki; Department of Health (J.K.), National Institute for Health and Welfare; and Institute for Molecular Medicine FIMM (J.K.), Helsinki, Finland.
  1. Correspondence to Dr. Korja: miikka.korja{at}hus.fi
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