Acute Zika infection with concurrent onset of Guillain-Barré Syndrome
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A 47-year-old Tongan male returning to New Zealand after a 2-week holiday in Tonga presented with 3 days of progressive limb weakness, numbness, unsteady gait, and dyspnea. Two days before departing Tonga (6 days before neurologic symptoms), he developed leg swelling with erythematous and pustular lesions, which were treated with flucloxacillin. He had no medical history, was not taking regular medication, and had a 20 pack-year smoking history.
Footnotes
Author contributions: Ronald Siu: drafted and edited the manuscript. Wajih Bukhari and Paul Timmings: reviewed and edited the manuscript. Angela Todd: performed real-time RT-PCR, interpreted the results, and critically reviewed the manuscript. Wendy Gunn: conducted serologic testing, interpreted the results, and critically reviewed the manuscript. Qiu Sue Huang: interpreted the results and critically reviewed the manuscript.
Study funding: No targeted funding reported.
Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.
- Received February 25, 2016.
- Accepted in final form June 28, 2016.
- © 2016 American Academy of Neurology
Letters: Rapid online correspondence
- Is rapid onset Zika virus Guillain-Barré syndrome a direct viral effect?
- Paul L. Timmings, MD, Neurologist, Paul.Timmings@xtra.co.nz
- Siu R. Bukhari W, Todd A, Gunn W,
Submitted January 31, 2017 - Zika virus-associated Guillain-Barré syndrome: Post-infectious or para-infectious complication?
- Patrick Gerardin, Clinician Researcher, INSERM CIC 1410, CHU de La Reunion, Saint Pierre, Reunion, France; UMR 134 PIMIT, Universite de La Rpatrick.gerardin@chu-reunion.fr
- V.M Cao-Lormeau, P. Tournebize, T. Cerny
Submitted January 24, 2017
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