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October 11, 2016; 87 (15) Clinical/Scientific Notes

Acute Zika infection with concurrent onset of Guillain-Barré Syndrome

Ronald Siu, Wajih Bukhari, Angela Todd, Wendy Gunn, Qiu Sue Huang, Paul Timmings
First published July 27, 2016, DOI: https://doi.org/10.1212/WNL.0000000000003038
Ronald Siu
From the Department of Neurology (R.S., W.B., P.T.), Waikato Hospital, Hamilton; and Arbovirus Reference Laboratory (A.T., W.G., Q.S.H.), Institute of Environmental Science and Research, Wellington, New Zealand.
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Wajih Bukhari
From the Department of Neurology (R.S., W.B., P.T.), Waikato Hospital, Hamilton; and Arbovirus Reference Laboratory (A.T., W.G., Q.S.H.), Institute of Environmental Science and Research, Wellington, New Zealand.
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Angela Todd
From the Department of Neurology (R.S., W.B., P.T.), Waikato Hospital, Hamilton; and Arbovirus Reference Laboratory (A.T., W.G., Q.S.H.), Institute of Environmental Science and Research, Wellington, New Zealand.
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Wendy Gunn
From the Department of Neurology (R.S., W.B., P.T.), Waikato Hospital, Hamilton; and Arbovirus Reference Laboratory (A.T., W.G., Q.S.H.), Institute of Environmental Science and Research, Wellington, New Zealand.
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Qiu Sue Huang
From the Department of Neurology (R.S., W.B., P.T.), Waikato Hospital, Hamilton; and Arbovirus Reference Laboratory (A.T., W.G., Q.S.H.), Institute of Environmental Science and Research, Wellington, New Zealand.
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Paul Timmings
From the Department of Neurology (R.S., W.B., P.T.), Waikato Hospital, Hamilton; and Arbovirus Reference Laboratory (A.T., W.G., Q.S.H.), Institute of Environmental Science and Research, Wellington, New Zealand.
MD
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Citation
Acute Zika infection with concurrent onset of Guillain-Barré Syndrome
Ronald Siu, Wajih Bukhari, Angela Todd, Wendy Gunn, Qiu Sue Huang, Paul Timmings
Neurology Oct 2016, 87 (15) 1623-1624; DOI: 10.1212/WNL.0000000000003038

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A 47-year-old Tongan male returning to New Zealand after a 2-week holiday in Tonga presented with 3 days of progressive limb weakness, numbness, unsteady gait, and dyspnea. Two days before departing Tonga (6 days before neurologic symptoms), he developed leg swelling with erythematous and pustular lesions, which were treated with flucloxacillin. He had no medical history, was not taking regular medication, and had a 20 pack-year smoking history.

Footnotes

  • Author contributions: Ronald Siu: drafted and edited the manuscript. Wajih Bukhari and Paul Timmings: reviewed and edited the manuscript. Angela Todd: performed real-time RT-PCR, interpreted the results, and critically reviewed the manuscript. Wendy Gunn: conducted serologic testing, interpreted the results, and critically reviewed the manuscript. Qiu Sue Huang: interpreted the results and critically reviewed the manuscript.

  • Study funding: No targeted funding reported.

  • Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.

  • Received February 25, 2016.
  • Accepted in final form June 28, 2016.
  • © 2016 American Academy of Neurology
View Full Text

Letters: Rapid online correspondence

  • Is rapid onset Zika virus Guillain-Barré syndrome a direct viral effect?
    • Paul L. Timmings, MD, Neurologist, Paul.Timmings@xtra.co.nz
    • Siu R. Bukhari W, Todd A, Gunn W,
    Submitted January 31, 2017
  • Zika virus-associated Guillain-Barré syndrome: Post-infectious or para-infectious complication?
    • Patrick Gerardin, Clinician Researcher, INSERM CIC 1410, CHU de La Reunion, Saint Pierre, Reunion, France; UMR 134 PIMIT, Universite de La Rpatrick.gerardin@chu-reunion.fr
    • V.M Cao-Lormeau, P. Tournebize, T. Cerny
    Submitted January 24, 2017
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